Vasoactive intestinal polypeptide and acetylcholine coexist with neuropeptide Y, dopamine-beta-hydroxylase, tyrosine hydroxylase, substance P or calcitonin gene-related peptide in neuronal subpopulations in cranial parasympathetic ganglia of rat
(1992) In Cell and Tissue Research 267(2). p.291-300- Abstract
- Immunohistochemistry has been used to demonstrate that neuropeptide Y, dopamine-beta-hydroxylase, calcitonin gene-related peptide or substance P are colocalized with vasoactive intestinal polypeptide and choline acetyltransferase in subpopulations of neurons in cranial parasympathetic ganglia of rat. These comprise the ciliary, sphenopalatine, otic, glossopharyngeal-vagal and internal carotid ganglia. In the ciliary and glossopharyngeal-vagal ganglia tyrosine hydroxylase is also found in such neurons. The findings emphasize that the combined localization of dopamine-beta-hydroxylase and neuropeptide Y or the presence of tyrosine hydroxylase is not exclusively a marker for peripheral adrenergic neurons. Further, the co-localization of... (More)
- Immunohistochemistry has been used to demonstrate that neuropeptide Y, dopamine-beta-hydroxylase, calcitonin gene-related peptide or substance P are colocalized with vasoactive intestinal polypeptide and choline acetyltransferase in subpopulations of neurons in cranial parasympathetic ganglia of rat. These comprise the ciliary, sphenopalatine, otic, glossopharyngeal-vagal and internal carotid ganglia. In the ciliary and glossopharyngeal-vagal ganglia tyrosine hydroxylase is also found in such neurons. The findings emphasize that the combined localization of dopamine-beta-hydroxylase and neuropeptide Y or the presence of tyrosine hydroxylase is not exclusively a marker for peripheral adrenergic neurons. Further, the co-localization of calcitonin gene-related peptide and substance P is not a decisive indication that a neuron is sensory in nature. It is discussed whether the presence of the enzymes and peptides other than vasoactive intestinal polypeptide is a remnant of a different expression during ontogenesis or indicates target-specific functions in the adult. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1106665
- author
- Hardebo, J E ; Suzuki, N ; Ekblad, E and Owman, Christer LU
- organization
- publishing date
- 1992
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Cell and Tissue Research
- volume
- 267
- issue
- 2
- pages
- 291 - 300
- publisher
- Springer
- external identifiers
-
- pmid:1350946
- scopus:0026564770
- ISSN
- 1432-0878
- language
- English
- LU publication?
- yes
- id
- 7a7b46e3-e4b8-4c1b-bb8b-823204e31abf (old id 1106665)
- date added to LUP
- 2016-04-01 12:03:04
- date last changed
- 2025-04-04 15:14:41
@article{7a7b46e3-e4b8-4c1b-bb8b-823204e31abf,
abstract = {{Immunohistochemistry has been used to demonstrate that neuropeptide Y, dopamine-beta-hydroxylase, calcitonin gene-related peptide or substance P are colocalized with vasoactive intestinal polypeptide and choline acetyltransferase in subpopulations of neurons in cranial parasympathetic ganglia of rat. These comprise the ciliary, sphenopalatine, otic, glossopharyngeal-vagal and internal carotid ganglia. In the ciliary and glossopharyngeal-vagal ganglia tyrosine hydroxylase is also found in such neurons. The findings emphasize that the combined localization of dopamine-beta-hydroxylase and neuropeptide Y or the presence of tyrosine hydroxylase is not exclusively a marker for peripheral adrenergic neurons. Further, the co-localization of calcitonin gene-related peptide and substance P is not a decisive indication that a neuron is sensory in nature. It is discussed whether the presence of the enzymes and peptides other than vasoactive intestinal polypeptide is a remnant of a different expression during ontogenesis or indicates target-specific functions in the adult.}},
author = {{Hardebo, J E and Suzuki, N and Ekblad, E and Owman, Christer}},
issn = {{1432-0878}},
language = {{eng}},
number = {{2}},
pages = {{291--300}},
publisher = {{Springer}},
series = {{Cell and Tissue Research}},
title = {{Vasoactive intestinal polypeptide and acetylcholine coexist with neuropeptide Y, dopamine-beta-hydroxylase, tyrosine hydroxylase, substance P or calcitonin gene-related peptide in neuronal subpopulations in cranial parasympathetic ganglia of rat}},
volume = {{267}},
year = {{1992}},
}