Red cell sodium-potassium adenosine triphosphatase sites and intracellular sodium increased in obese school children
(1992) In Mineral and Electrolyte Metabolism 18(1). p.6-8- Abstract
- Principally to ascertain whether mineral metabolism is involved in weight regulation, the 40 most obese of 1,774 children, aged 10-11 years, screened for obesity were compared with 46 age-matched controls. The obese children had more 3H-Ouabain erythrocyte binding sites (p = 0.04), higher intracellular sodium (p = 0.04), and lower plasma sodium (p = 0.002). After exclusion of the non-Scandinavians, the p values were p = 0.02, p = 0.03, and p = 0.03, respectively. Analysis of variance also showed the differences to be more dependent on obesity than on gender or nationality. It is concluded that obese children have more 3H-Ouabain erythrocyte binding sites indicating an increase of the sodium-potassium adenosine triphosphatase activity. The... (More)
- Principally to ascertain whether mineral metabolism is involved in weight regulation, the 40 most obese of 1,774 children, aged 10-11 years, screened for obesity were compared with 46 age-matched controls. The obese children had more 3H-Ouabain erythrocyte binding sites (p = 0.04), higher intracellular sodium (p = 0.04), and lower plasma sodium (p = 0.002). After exclusion of the non-Scandinavians, the p values were p = 0.02, p = 0.03, and p = 0.03, respectively. Analysis of variance also showed the differences to be more dependent on obesity than on gender or nationality. It is concluded that obese children have more 3H-Ouabain erythrocyte binding sites indicating an increase of the sodium-potassium adenosine triphosphatase activity. The increase of intracellular sodium may increase the risk of future hypertension. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1106803
- author
- Flodmark, Carl-Erik LU ; Henningsen, N.C. and Sveger, T.
- organization
- publishing date
- 1992
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Mineral and Electrolyte Metabolism
- volume
- 18
- issue
- 1
- pages
- 6 - 8
- publisher
- Karger
- external identifiers
-
- scopus:0026494091
- ISSN
- 1423-016X
- language
- English
- LU publication?
- yes
- id
- aab89ce5-faae-4026-9d41-1f7b570c7d1d (old id 1106803)
- date added to LUP
- 2016-04-01 11:52:58
- date last changed
- 2025-04-04 14:30:26
@article{aab89ce5-faae-4026-9d41-1f7b570c7d1d,
abstract = {{Principally to ascertain whether mineral metabolism is involved in weight regulation, the 40 most obese of 1,774 children, aged 10-11 years, screened for obesity were compared with 46 age-matched controls. The obese children had more 3H-Ouabain erythrocyte binding sites (p = 0.04), higher intracellular sodium (p = 0.04), and lower plasma sodium (p = 0.002). After exclusion of the non-Scandinavians, the p values were p = 0.02, p = 0.03, and p = 0.03, respectively. Analysis of variance also showed the differences to be more dependent on obesity than on gender or nationality. It is concluded that obese children have more 3H-Ouabain erythrocyte binding sites indicating an increase of the sodium-potassium adenosine triphosphatase activity. The increase of intracellular sodium may increase the risk of future hypertension.}},
author = {{Flodmark, Carl-Erik and Henningsen, N.C. and Sveger, T.}},
issn = {{1423-016X}},
language = {{eng}},
number = {{1}},
pages = {{6--8}},
publisher = {{Karger}},
series = {{Mineral and Electrolyte Metabolism}},
title = {{Red cell sodium-potassium adenosine triphosphatase sites and intracellular sodium increased in obese school children}},
volume = {{18}},
year = {{1992}},
}