Expression of the Arp protein, a member of the M protein family, is not sufficient to inhibit phagocytosis of Streptococcus pyogenes
(1995) In Infection and Immunity 63(1). p.345-348- Abstract
- Many Streptococcus pyogenes immunoglobulin-binding proteins have structural similarities to the antiphagocytic M protein, including the well-known C repeats. One of these molecules is the immunoglobulin A-binding protein Arp, which is expressed by a serotype 4 strain for which no antiphagocytic M protein has yet been described. We expressed Arp4 in an S. pyogenes strain from which the structural gene for the M protein has been deleted and found that Arp4 is not sufficient to inhibit phagocytosis.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1109102
- author
- Husmann, Linda K ; Scott, June R ; Lindahl, Gunnar LU and Stenberg, Lars LU
- organization
- publishing date
- 1995
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Infection and Immunity
- volume
- 63
- issue
- 1
- pages
- 345 - 348
- publisher
- American Society for Microbiology
- external identifiers
-
- pmid:7806375
- scopus:0028855515
- ISSN
- 1098-5522
- language
- English
- LU publication?
- yes
- id
- a900b6a1-6703-4cf5-b66c-0e4a3b8d9b9d (old id 1109102)
- alternative location
- http://iai.highwire.org/cgi/reprint/63/1/345
- date added to LUP
- 2016-04-01 11:41:50
- date last changed
- 2021-04-18 03:45:28
@article{a900b6a1-6703-4cf5-b66c-0e4a3b8d9b9d, abstract = {{Many Streptococcus pyogenes immunoglobulin-binding proteins have structural similarities to the antiphagocytic M protein, including the well-known C repeats. One of these molecules is the immunoglobulin A-binding protein Arp, which is expressed by a serotype 4 strain for which no antiphagocytic M protein has yet been described. We expressed Arp4 in an S. pyogenes strain from which the structural gene for the M protein has been deleted and found that Arp4 is not sufficient to inhibit phagocytosis.}}, author = {{Husmann, Linda K and Scott, June R and Lindahl, Gunnar and Stenberg, Lars}}, issn = {{1098-5522}}, language = {{eng}}, number = {{1}}, pages = {{345--348}}, publisher = {{American Society for Microbiology}}, series = {{Infection and Immunity}}, title = {{Expression of the Arp protein, a member of the M protein family, is not sufficient to inhibit phagocytosis of Streptococcus pyogenes}}, url = {{http://iai.highwire.org/cgi/reprint/63/1/345}}, volume = {{63}}, year = {{1995}}, }