High-grade non-Hodgkin's lymphoma stage I. A retrospective study of treatment, outcome and prognostic factors in 213 patients
(1996) In Acta Oncologica 35(2). p.171-177- Abstract
- In a retrospective study of 213 patients with high-grade non-Hodgkin's lymphomas clinical stage I, diagnosed 1985-1990, pretreatment prognostic variables and result of treatment were analysed. The median age of the patients was 67 years. Treatment consisted of radiotherapy in 61%, chemotherapy (10%) chemotherapy followed by radiotherapy (23%) and surgery alone (5%) of the patients. Complete response was achieved in 89% of the patients with estimated relapse-free survival at 5 years of 73%. Relative 5-year survival of all patients was 73%. After chemotherapy followed by radiotherapy the relapse rate was 15% compared with 29% after radiotherapy only. The 5-year relative survival differed between 58% and 74% in the treatment groups. Age, sex,... (More)
- In a retrospective study of 213 patients with high-grade non-Hodgkin's lymphomas clinical stage I, diagnosed 1985-1990, pretreatment prognostic variables and result of treatment were analysed. The median age of the patients was 67 years. Treatment consisted of radiotherapy in 61%, chemotherapy (10%) chemotherapy followed by radiotherapy (23%) and surgery alone (5%) of the patients. Complete response was achieved in 89% of the patients with estimated relapse-free survival at 5 years of 73%. Relative 5-year survival of all patients was 73%. After chemotherapy followed by radiotherapy the relapse rate was 15% compared with 29% after radiotherapy only. The 5-year relative survival differed between 58% and 74% in the treatment groups. Age, sex, nodal versus extranodal lymphoma, systemic symptoms, bulk of tumor and level of serum lactic dehydrogenase (s-LDH) were analysed as prognostic factors. In multivariate variate analysis, only age 65 years or older and elevated s-LDH were significant independent adverse prognostic factors. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1110140
- author
- Osterman, Birgitta ; Cavallin-Ståhl, Eva LU ; Hagberg, H ; Lindén, Ola LU and Lenner, Per
- organization
- publishing date
- 1996
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Acta Oncologica
- volume
- 35
- issue
- 2
- pages
- 171 - 177
- publisher
- Taylor & Francis
- external identifiers
-
- pmid:8639312
- scopus:0029885997
- ISSN
- 1651-226X
- DOI
- 10.3109/02841869609098498
- language
- English
- LU publication?
- yes
- id
- ba01b9cf-b830-4456-9080-7e4b196cb34a (old id 1110140)
- date added to LUP
- 2016-04-01 16:05:00
- date last changed
- 2022-01-28 17:11:43
@article{ba01b9cf-b830-4456-9080-7e4b196cb34a, abstract = {{In a retrospective study of 213 patients with high-grade non-Hodgkin's lymphomas clinical stage I, diagnosed 1985-1990, pretreatment prognostic variables and result of treatment were analysed. The median age of the patients was 67 years. Treatment consisted of radiotherapy in 61%, chemotherapy (10%) chemotherapy followed by radiotherapy (23%) and surgery alone (5%) of the patients. Complete response was achieved in 89% of the patients with estimated relapse-free survival at 5 years of 73%. Relative 5-year survival of all patients was 73%. After chemotherapy followed by radiotherapy the relapse rate was 15% compared with 29% after radiotherapy only. The 5-year relative survival differed between 58% and 74% in the treatment groups. Age, sex, nodal versus extranodal lymphoma, systemic symptoms, bulk of tumor and level of serum lactic dehydrogenase (s-LDH) were analysed as prognostic factors. In multivariate variate analysis, only age 65 years or older and elevated s-LDH were significant independent adverse prognostic factors.}}, author = {{Osterman, Birgitta and Cavallin-Ståhl, Eva and Hagberg, H and Lindén, Ola and Lenner, Per}}, issn = {{1651-226X}}, language = {{eng}}, number = {{2}}, pages = {{171--177}}, publisher = {{Taylor & Francis}}, series = {{Acta Oncologica}}, title = {{High-grade non-Hodgkin's lymphoma stage I. A retrospective study of treatment, outcome and prognostic factors in 213 patients}}, url = {{http://dx.doi.org/10.3109/02841869609098498}}, doi = {{10.3109/02841869609098498}}, volume = {{35}}, year = {{1996}}, }