New world, but not Old World, monkeys carry several genes encoding beta-microseminoprotein
(1999) In European Journal of Biochemistry 264(2). p.407-414- Abstract
- It was shown by Southern hybridization that cotton-top tamarin and common marmoset, New World monkeys, carry three or more genes encoding beta-microseminoprotein, also known as PSP94. In contrast, the genomes of Old World monkeys, as represented by rhesus macaque and sacred baboon, contain a single gene. Clones containing three different genes encoding beta-microseminoprotein were isolated from a cotton-top tamarin genomic library. They carry two complete genes of four exons and a third gene lacking the first exon. The structure suggests that the three genes are functionally active and give rise to transcripts that are approximately 86% similar in sequence. By sequencing one gene in full, it was shown that the introns carry an excess of... (More)
- It was shown by Southern hybridization that cotton-top tamarin and common marmoset, New World monkeys, carry three or more genes encoding beta-microseminoprotein, also known as PSP94. In contrast, the genomes of Old World monkeys, as represented by rhesus macaque and sacred baboon, contain a single gene. Clones containing three different genes encoding beta-microseminoprotein were isolated from a cotton-top tamarin genomic library. They carry two complete genes of four exons and a third gene lacking the first exon. The structure suggests that the three genes are functionally active and give rise to transcripts that are approximately 86% similar in sequence. By sequencing one gene in full, it was shown that the introns carry an excess of interspersed repeats, on average 29% of the introns consist of Alu repeats. A phylogenetic analysis demonstrated that the genes probably arose in New World monkeys after the separation from Old World primates. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1115112
- author
- Makinen, M ; Valtonen-André, Camilla LU and Lundwall, Åke LU
- organization
- publishing date
- 1999
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- mucous, evolution, prostate, semen
- in
- European Journal of Biochemistry
- volume
- 264
- issue
- 2
- pages
- 407 - 414
- publisher
- Wiley-Blackwell
- external identifiers
-
- pmid:10491085
- scopus:0033199569
- ISSN
- 0014-2956
- language
- English
- LU publication?
- yes
- id
- c77e352f-1eed-4f51-8c67-ad247f87b6ab (old id 1115112)
- alternative location
- http://www.ingentaconnect.com/content/bsc/ejb/1999/00000264/00000002/art00614
- date added to LUP
- 2016-04-01 16:41:49
- date last changed
- 2022-01-28 21:28:37
@article{c77e352f-1eed-4f51-8c67-ad247f87b6ab, abstract = {{It was shown by Southern hybridization that cotton-top tamarin and common marmoset, New World monkeys, carry three or more genes encoding beta-microseminoprotein, also known as PSP94. In contrast, the genomes of Old World monkeys, as represented by rhesus macaque and sacred baboon, contain a single gene. Clones containing three different genes encoding beta-microseminoprotein were isolated from a cotton-top tamarin genomic library. They carry two complete genes of four exons and a third gene lacking the first exon. The structure suggests that the three genes are functionally active and give rise to transcripts that are approximately 86% similar in sequence. By sequencing one gene in full, it was shown that the introns carry an excess of interspersed repeats, on average 29% of the introns consist of Alu repeats. A phylogenetic analysis demonstrated that the genes probably arose in New World monkeys after the separation from Old World primates.}}, author = {{Makinen, M and Valtonen-André, Camilla and Lundwall, Åke}}, issn = {{0014-2956}}, keywords = {{mucous; evolution; prostate; semen}}, language = {{eng}}, number = {{2}}, pages = {{407--414}}, publisher = {{Wiley-Blackwell}}, series = {{European Journal of Biochemistry}}, title = {{New world, but not Old World, monkeys carry several genes encoding beta-microseminoprotein}}, url = {{http://www.ingentaconnect.com/content/bsc/ejb/1999/00000264/00000002/art00614}}, volume = {{264}}, year = {{1999}}, }