The diagnosis of bacterial vaginosis and vaginal flora changes
(2001) In Archives of Gynecology and Obstetrics 265(1). p.11-15- Abstract
- In a population of 956 women, attending for contraceptive advice, 131 (13.7%) were found to have BV acording to Amsel's criteria. Clue cells were detected in 200 (20.9%) women, a positive amine ('sniff') test in 191 (20.0%), a vaginal pH > or = 4.7 in 243 (25.4%) and a "characteristic" vaginal discharge in 104 (10.9%) women. Sensitivity, specificity, positive and negative predictive values in relation to BV were calculated for each of these four criteria. The detection of clue cells, an increased pH and a positive sniff test showed excellent sensitivity (86-100%) values, but had a less satisfactory positive predictive value (52-68%). Vaginal discharge was found to be a poor predictor of BV. The vaginal flora in women with clue cells,... (More)
- In a population of 956 women, attending for contraceptive advice, 131 (13.7%) were found to have BV acording to Amsel's criteria. Clue cells were detected in 200 (20.9%) women, a positive amine ('sniff') test in 191 (20.0%), a vaginal pH > or = 4.7 in 243 (25.4%) and a "characteristic" vaginal discharge in 104 (10.9%) women. Sensitivity, specificity, positive and negative predictive values in relation to BV were calculated for each of these four criteria. The detection of clue cells, an increased pH and a positive sniff test showed excellent sensitivity (86-100%) values, but had a less satisfactory positive predictive value (52-68%). Vaginal discharge was found to be a poor predictor of BV. The vaginal flora in women with clue cells, increased vaginal pH or a positive sniff test was very similar to that of the women with BV, every after excluding concomitant cases of BV and the three respective criteria. Thus, a positive amine test, which is easily performed, strongly suggests BV and a vaginal flora predominated by Gardnerella vaginalis, Mycoplasma hominis, Mobiluncus species and anaerobic species on one hand, and lack of lactobacilli on the other. When there is a clinical suspicion of BV, the sniff test is positive and differential diagnoses are excluded, one can safely treat a woman for bacterial vaginosis. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1122838
- author
- Hellberg, D ; Nilsson, S and Mårdh, Per-Anders LU
- organization
- publishing date
- 2001
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Bacterial vaginosis, Amine test, Bacteria, Diagnosis
- in
- Archives of Gynecology and Obstetrics
- volume
- 265
- issue
- 1
- pages
- 11 - 15
- publisher
- Springer
- external identifiers
-
- pmid:11327086
- scopus:0035083024
- ISSN
- 1432-0711
- DOI
- 10.1007/s004040000109
- language
- English
- LU publication?
- yes
- id
- 17d0a07c-f55d-4a3a-8461-4d0f6a644653 (old id 1122838)
- date added to LUP
- 2016-04-01 12:05:29
- date last changed
- 2022-01-26 22:40:46
@article{17d0a07c-f55d-4a3a-8461-4d0f6a644653,
abstract = {{In a population of 956 women, attending for contraceptive advice, 131 (13.7%) were found to have BV acording to Amsel's criteria. Clue cells were detected in 200 (20.9%) women, a positive amine ('sniff') test in 191 (20.0%), a vaginal pH > or = 4.7 in 243 (25.4%) and a "characteristic" vaginal discharge in 104 (10.9%) women. Sensitivity, specificity, positive and negative predictive values in relation to BV were calculated for each of these four criteria. The detection of clue cells, an increased pH and a positive sniff test showed excellent sensitivity (86-100%) values, but had a less satisfactory positive predictive value (52-68%). Vaginal discharge was found to be a poor predictor of BV. The vaginal flora in women with clue cells, increased vaginal pH or a positive sniff test was very similar to that of the women with BV, every after excluding concomitant cases of BV and the three respective criteria. Thus, a positive amine test, which is easily performed, strongly suggests BV and a vaginal flora predominated by Gardnerella vaginalis, Mycoplasma hominis, Mobiluncus species and anaerobic species on one hand, and lack of lactobacilli on the other. When there is a clinical suspicion of BV, the sniff test is positive and differential diagnoses are excluded, one can safely treat a woman for bacterial vaginosis.}},
author = {{Hellberg, D and Nilsson, S and Mårdh, Per-Anders}},
issn = {{1432-0711}},
keywords = {{Bacterial vaginosis; Amine test; Bacteria; Diagnosis}},
language = {{eng}},
number = {{1}},
pages = {{11--15}},
publisher = {{Springer}},
series = {{Archives of Gynecology and Obstetrics}},
title = {{The diagnosis of bacterial vaginosis and vaginal flora changes}},
url = {{http://dx.doi.org/10.1007/s004040000109}},
doi = {{10.1007/s004040000109}},
volume = {{265}},
year = {{2001}},
}