Blood velocity in the fetal vein of Galen and the outcome of high-risk pregnancy
(2001) In European Journal of Obstetrics, Gynecology, and Reproductive Biology 99(1). p.14-18- Abstract
- BACKGROUND: Pulsation in the flow velocity waveform in the umbilical vein is related to perinatal mortality but the flow velocity waveform in the fetal vein of Galen is normally even and without fluctuation. OBJECTIVES: To establish whether blood flow velocity pulsations in the vein of Galen in high-risk pregnancies are related to outcome. STUDY DESIGN: The vein of Galen was located by colour Doppler ultrasound in 102 pregnancies complicated by severe pregnancy-induced hypertension. The blood velocity waveform was recorded by pulsed Doppler within 2 days of delivery and the presence pulsations related to pregnancy outcome, including emergency operative intervention and neonatal distress. Umbilical artery and vein and uterine artery blood... (More)
- BACKGROUND: Pulsation in the flow velocity waveform in the umbilical vein is related to perinatal mortality but the flow velocity waveform in the fetal vein of Galen is normally even and without fluctuation. OBJECTIVES: To establish whether blood flow velocity pulsations in the vein of Galen in high-risk pregnancies are related to outcome. STUDY DESIGN: The vein of Galen was located by colour Doppler ultrasound in 102 pregnancies complicated by severe pregnancy-induced hypertension. The blood velocity waveform was recorded by pulsed Doppler within 2 days of delivery and the presence pulsations related to pregnancy outcome, including emergency operative intervention and neonatal distress. Umbilical artery and vein and uterine artery blood flow velocity waveform were also recorded at the same time. The clinicians managing the women were unaware of the venous flow results. RESULTS: Pulsation were present in the vein of Galen in 68 cases and in the umbilical vein in 21. Both were significantly related to adverse outcome. Pulsations in the vein of Galen were seen in all seven perinatal deaths. CONCLUSIONS: Since umbilical venous pulsation are a late sign of fetal compromise, and pulsations in the vein of Galen seem to appear earlier, thus being an intermediate sign of fetal compromise that might be of great value for fetal surveillance. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1122990
- author
- Dubiel, Mariusz ; Breborowicz, Grzegorz H. ; Laurini, Ricardo LU and Gudmundsson, Saemundur LU
- organization
- publishing date
- 2001
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Vein of Galen, Doppler ultrasound, Umbilical vein, Pregnancy
- in
- European Journal of Obstetrics, Gynecology, and Reproductive Biology
- volume
- 99
- issue
- 1
- pages
- 14 - 18
- publisher
- Elsevier
- external identifiers
-
- pmid:11604180
- scopus:0034790772
- ISSN
- 0301-2115
- DOI
- 10.1016/S0301-2115(01)00340-2
- language
- English
- LU publication?
- yes
- id
- 1f826e2a-264d-460d-8977-f9d8fcdbaf3c (old id 1122990)
- date added to LUP
- 2016-04-01 12:16:10
- date last changed
- 2022-01-27 01:17:28
@article{1f826e2a-264d-460d-8977-f9d8fcdbaf3c, abstract = {{BACKGROUND: Pulsation in the flow velocity waveform in the umbilical vein is related to perinatal mortality but the flow velocity waveform in the fetal vein of Galen is normally even and without fluctuation. OBJECTIVES: To establish whether blood flow velocity pulsations in the vein of Galen in high-risk pregnancies are related to outcome. STUDY DESIGN: The vein of Galen was located by colour Doppler ultrasound in 102 pregnancies complicated by severe pregnancy-induced hypertension. The blood velocity waveform was recorded by pulsed Doppler within 2 days of delivery and the presence pulsations related to pregnancy outcome, including emergency operative intervention and neonatal distress. Umbilical artery and vein and uterine artery blood flow velocity waveform were also recorded at the same time. The clinicians managing the women were unaware of the venous flow results. RESULTS: Pulsation were present in the vein of Galen in 68 cases and in the umbilical vein in 21. Both were significantly related to adverse outcome. Pulsations in the vein of Galen were seen in all seven perinatal deaths. CONCLUSIONS: Since umbilical venous pulsation are a late sign of fetal compromise, and pulsations in the vein of Galen seem to appear earlier, thus being an intermediate sign of fetal compromise that might be of great value for fetal surveillance.}}, author = {{Dubiel, Mariusz and Breborowicz, Grzegorz H. and Laurini, Ricardo and Gudmundsson, Saemundur}}, issn = {{0301-2115}}, keywords = {{Vein of Galen; Doppler ultrasound; Umbilical vein; Pregnancy}}, language = {{eng}}, number = {{1}}, pages = {{14--18}}, publisher = {{Elsevier}}, series = {{European Journal of Obstetrics, Gynecology, and Reproductive Biology}}, title = {{Blood velocity in the fetal vein of Galen and the outcome of high-risk pregnancy}}, url = {{http://dx.doi.org/10.1016/S0301-2115(01)00340-2}}, doi = {{10.1016/S0301-2115(01)00340-2}}, volume = {{99}}, year = {{2001}}, }