Role du paracetamol dans la prise en charge des douleurs aigues
(2003) In Drugs 63(Special Issue 2). p.15-22- Abstract
- Paracetamol (acetaminophen) has been shown to be an effective analgesic for the treatment of moderate pain where it is chiefly indicated, as shown in placebo-controlled studies in the perioperative setting and other acute pain states. In addition, an opioid-sparing effect has been demonstrated. No clinically relevant adverse effects are usually apparent with recommended doses. Paracetamol is an effective component in 'multimodal analgesia' in combination with morphine, weak opioids and non-steroidal anti-inflammatory drugs. Although most studies involve the perioperative setting, similar results have been obtained in other acute pain states, such as acute musculoskeletal pain, migraine, etc. In conclusion, paracetamol has a favourable... (More)
- Paracetamol (acetaminophen) has been shown to be an effective analgesic for the treatment of moderate pain where it is chiefly indicated, as shown in placebo-controlled studies in the perioperative setting and other acute pain states. In addition, an opioid-sparing effect has been demonstrated. No clinically relevant adverse effects are usually apparent with recommended doses. Paracetamol is an effective component in 'multimodal analgesia' in combination with morphine, weak opioids and non-steroidal anti-inflammatory drugs. Although most studies involve the perioperative setting, similar results have been obtained in other acute pain states, such as acute musculoskeletal pain, migraine, etc. In conclusion, paracetamol has a favourable efficacy-tolerability profile and is therefore recommended as a basic, first-line analgesic in acute pain states and as a valuable component in multimodal analgesia. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1128098
- author
- Kehlet, Henrik and Werner, Mads LU
- alternative title
- [Role of paracetamol in the acute pain management]
- publishing date
- 2003
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Drugs
- volume
- 63
- issue
- Special Issue 2
- pages
- 15 - 22
- publisher
- Adis International
- external identifiers
-
- pmid:14758787
- scopus:0142147054
- ISSN
- 0012-6667
- language
- French
- LU publication?
- no
- id
- 82a2adbf-aba2-421c-afe5-14b718c539da (old id 1128098)
- date added to LUP
- 2016-04-01 15:36:45
- date last changed
- 2022-03-07 00:30:26
@article{82a2adbf-aba2-421c-afe5-14b718c539da,
abstract = {{Paracetamol (acetaminophen) has been shown to be an effective analgesic for the treatment of moderate pain where it is chiefly indicated, as shown in placebo-controlled studies in the perioperative setting and other acute pain states. In addition, an opioid-sparing effect has been demonstrated. No clinically relevant adverse effects are usually apparent with recommended doses. Paracetamol is an effective component in 'multimodal analgesia' in combination with morphine, weak opioids and non-steroidal anti-inflammatory drugs. Although most studies involve the perioperative setting, similar results have been obtained in other acute pain states, such as acute musculoskeletal pain, migraine, etc. In conclusion, paracetamol has a favourable efficacy-tolerability profile and is therefore recommended as a basic, first-line analgesic in acute pain states and as a valuable component in multimodal analgesia.}},
author = {{Kehlet, Henrik and Werner, Mads}},
issn = {{0012-6667}},
language = {{fre}},
number = {{Special Issue 2}},
pages = {{15--22}},
publisher = {{Adis International}},
series = {{Drugs}},
title = {{Role du paracetamol dans la prise en charge des douleurs aigues}},
volume = {{63}},
year = {{2003}},
}