Corneal epithelial keratitis in herpes zoster ophthalmicus: "delayed" and "sine herpete". A non-contact photomicrographic in vivo study in the human cornea.
(2002) In European Journal of Ophthalmology 12(4). p.267-275- Abstract
- PURPOSE. To investigate the origin of corneal epithelial keratitis occurring without accompanying herpes zoster ophthalmicus (HZO) cutaneous rash. METHODS. Corneal epithelial lesions in seven patients (four with a history of classical HZO with cutaneous rash, one of herpes zoster oticus, and two with no history of herpes zoster, were examined with the slit lamp and photographed by non-contact in vivo photomicrography. The findings were compared with lesions in classical acute HZO. Polymerase chain reaction (PCR) was done in three patients. RESULTS. Slit lamp appearance, morphology at higher magnification, and kinetics of the lesions were indistinguishable from classical acute HZO. PCR was positive for varicella-zoster virus DNA in all... (More)
- PURPOSE. To investigate the origin of corneal epithelial keratitis occurring without accompanying herpes zoster ophthalmicus (HZO) cutaneous rash. METHODS. Corneal epithelial lesions in seven patients (four with a history of classical HZO with cutaneous rash, one of herpes zoster oticus, and two with no history of herpes zoster, were examined with the slit lamp and photographed by non-contact in vivo photomicrography. The findings were compared with lesions in classical acute HZO. Polymerase chain reaction (PCR) was done in three patients. RESULTS. Slit lamp appearance, morphology at higher magnification, and kinetics of the lesions were indistinguishable from classical acute HZO. PCR was positive for varicella-zoster virus DNA in all three samples. CONCLUSIONS. The findings strongly suggest that HZO typical corneal epithelial lesions occurring in the absence of cutaneous rash are in fact recurrent episodes of virus shedding. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/114893
- author
- Tabery, Helena LU
- organization
- publishing date
- 2002
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Corneal: virology, Herpesvirus 3, Human, Keratitis, Human: genetics, Human: isolation & purification, Herpetic: pathology, Zoster Sine Herpete: virology, Recurrence, Support, Non-U.S. Gov't, Virus Shedding: physiology, Zoster Sine Herpete: pathology, Polymerase Chain Reaction, Middle Age, Male, Herpetic: virology, Female, Herpes Zoster Ophthalmicus: pathology, Herpes Zoster Ophthalmicus: virology, Herpes Zoster Oticus: pathology, Herpes Zoster Oticus: virology, Corneal: pathology, Epithelium, Viral: analysis, Aged, 80 and over, Case Report, Comparative Study, DNA
- in
- European Journal of Ophthalmology
- volume
- 12
- issue
- 4
- pages
- 267 - 275
- publisher
- Wichtig Editore
- external identifiers
-
- wos:000177771800003
- scopus:0036657382
- ISSN
- 1120-6721
- language
- English
- LU publication?
- yes
- id
- 1e3d1ea1-ba9e-4256-9e59-b4048b8834e5 (old id 114893)
- alternative location
- http://www.eur-j-ophthalmol.com/ejo/index.asp?a=abstract&id=48812DD6-B1B4-11D6-9FAE-006097F
- date added to LUP
- 2016-04-01 11:52:10
- date last changed
- 2022-01-26 19:26:06
@article{1e3d1ea1-ba9e-4256-9e59-b4048b8834e5,
abstract = {{PURPOSE. To investigate the origin of corneal epithelial keratitis occurring without accompanying herpes zoster ophthalmicus (HZO) cutaneous rash. METHODS. Corneal epithelial lesions in seven patients (four with a history of classical HZO with cutaneous rash, one of herpes zoster oticus, and two with no history of herpes zoster, were examined with the slit lamp and photographed by non-contact in vivo photomicrography. The findings were compared with lesions in classical acute HZO. Polymerase chain reaction (PCR) was done in three patients. RESULTS. Slit lamp appearance, morphology at higher magnification, and kinetics of the lesions were indistinguishable from classical acute HZO. PCR was positive for varicella-zoster virus DNA in all three samples. CONCLUSIONS. The findings strongly suggest that HZO typical corneal epithelial lesions occurring in the absence of cutaneous rash are in fact recurrent episodes of virus shedding.}},
author = {{Tabery, Helena}},
issn = {{1120-6721}},
keywords = {{Corneal: virology; Herpesvirus 3; Human; Keratitis; Human: genetics; Human: isolation & purification; Herpetic: pathology; Zoster Sine Herpete: virology; Recurrence; Support; Non-U.S. Gov't; Virus Shedding: physiology; Zoster Sine Herpete: pathology; Polymerase Chain Reaction; Middle Age; Male; Herpetic: virology; Female; Herpes Zoster Ophthalmicus: pathology; Herpes Zoster Ophthalmicus: virology; Herpes Zoster Oticus: pathology; Herpes Zoster Oticus: virology; Corneal: pathology; Epithelium; Viral: analysis; Aged; 80 and over; Case Report; Comparative Study; DNA}},
language = {{eng}},
number = {{4}},
pages = {{267--275}},
publisher = {{Wichtig Editore}},
series = {{European Journal of Ophthalmology}},
title = {{Corneal epithelial keratitis in herpes zoster ophthalmicus: "delayed" and "sine herpete". A non-contact photomicrographic in vivo study in the human cornea.}},
url = {{http://www.eur-j-ophthalmol.com/ejo/index.asp?a=abstract&id=48812DD6-B1B4-11D6-9FAE-006097F}},
volume = {{12}},
year = {{2002}},
}