Effect of Dynamic Channelling on the Transient-state Kinetics of Coupled Enzyme Reactions
(1999) In Journal of Theoretical Biology 198(1). p.135-141- Abstract
- Evidence is presented to show that the presence of a channelled reaction branch in a coupled two-enzyme reaction leads to a slower overall relaxation of the system towards steady state following perturbations of the reaction conditions. A predominant part of the total reaction flux change resulting from perturbations may be governed by transients that are more rapid in the presence than in the absence of a channel, but only under specific conditions that are not likely to be of biological relevance.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/125393
- author
- Pettersson, Gösta LU
- organization
- publishing date
- 1999
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Theoretical Biology
- volume
- 198
- issue
- 1
- pages
- 135 - 141
- publisher
- Academic Press
- external identifiers
-
- scopus:0033532136
- ISSN
- 1095-8541
- DOI
- 10.1006/jtbi.1999.0904
- language
- English
- LU publication?
- yes
- id
- 34ab10a3-472c-433e-9a34-e17509f0809b (old id 125393)
- date added to LUP
- 2016-04-01 15:25:23
- date last changed
- 2022-01-28 05:16:10
@article{34ab10a3-472c-433e-9a34-e17509f0809b, abstract = {{Evidence is presented to show that the presence of a channelled reaction branch in a coupled two-enzyme reaction leads to a slower overall relaxation of the system towards steady state following perturbations of the reaction conditions. A predominant part of the total reaction flux change resulting from perturbations may be governed by transients that are more rapid in the presence than in the absence of a channel, but only under specific conditions that are not likely to be of biological relevance.}}, author = {{Pettersson, Gösta}}, issn = {{1095-8541}}, language = {{eng}}, number = {{1}}, pages = {{135--141}}, publisher = {{Academic Press}}, series = {{Journal of Theoretical Biology}}, title = {{Effect of Dynamic Channelling on the Transient-state Kinetics of Coupled Enzyme Reactions}}, url = {{http://dx.doi.org/10.1006/jtbi.1999.0904}}, doi = {{10.1006/jtbi.1999.0904}}, volume = {{198}}, year = {{1999}}, }