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Statistical Analysis Plan (SAP) for the KANON-Study

Frobell, Richard LU (2008)
Abstract
STUDY SYNOPSIS

Anterior cruciate ligament (ACL) injuries are common, severe and disabling knee injuries occurring in young active athletes. Treatment could be either surgical or non-surgical,both involving extensive rehabilitation for at least 4-6 months. Two RCTs comparing surgical and non-surgical treatment of ACL injured knees was performed in the 80’s and both failed to present any difference between the two treatment groups [1, 2].

Approximately 150 000 surgical reconstructions are performed annually in the US alone with an estimated cost of more than 2 billion dollars including the postoperative rehabilitation [3, 4]. This study was designed to investigate in a randomized, controlled trial whether the outcome of... (More)
STUDY SYNOPSIS

Anterior cruciate ligament (ACL) injuries are common, severe and disabling knee injuries occurring in young active athletes. Treatment could be either surgical or non-surgical,both involving extensive rehabilitation for at least 4-6 months. Two RCTs comparing surgical and non-surgical treatment of ACL injured knees was performed in the 80’s and both failed to present any difference between the two treatment groups [1, 2].

Approximately 150 000 surgical reconstructions are performed annually in the US alone with an estimated cost of more than 2 billion dollars including the postoperative rehabilitation [3, 4]. This study was designed to investigate in a randomized, controlled trial whether the outcome of treatment according to a rehabilitation program after acute ACL disruption improved by adding ACL reconstruction. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Book/Report
publication status
unpublished
subject
pages
20 pages
publisher
Department of Orthopaedics, Lund University
language
English
LU publication?
yes
id
39d9df6e-36e3-4da4-8445-8436400ba07d (old id 1276774)
date added to LUP
2016-04-04 10:43:41
date last changed
2018-11-21 21:00:26
@techreport{39d9df6e-36e3-4da4-8445-8436400ba07d,
  abstract     = {{STUDY SYNOPSIS<br/><br>
Anterior cruciate ligament (ACL) injuries are common, severe and disabling knee injuries occurring in young active athletes. Treatment could be either surgical or non-surgical,both involving extensive rehabilitation for at least 4-6 months. Two RCTs comparing surgical and non-surgical treatment of ACL injured knees was performed in the 80’s and both failed to present any difference between the two treatment groups [1, 2].<br/><br>
Approximately 150 000 surgical reconstructions are performed annually in the US alone with an estimated cost of more than 2 billion dollars including the postoperative rehabilitation [3, 4]. This study was designed to investigate in a randomized, controlled trial whether the outcome of treatment according to a rehabilitation program after acute ACL disruption improved by adding ACL reconstruction.}},
  author       = {{Frobell, Richard}},
  institution  = {{Department of Orthopaedics, Lund University}},
  language     = {{eng}},
  title        = {{Statistical Analysis Plan (SAP) for the KANON-Study}},
  url          = {{https://lup.lub.lu.se/search/files/5607703/1276775.pdf}},
  year         = {{2008}},
}