Differences in genetic and transcriptional organization of the glpTQ operons between Haemophilus influenzae type b and nontypeable strains
(2003) In Journal of Bacteriology 185(24). p.7285-7290- Abstract
- The glpTQ operon of Haemophilus influenzae type b (Hib) and nontypeable H. influenzae (NTHi) strains is highly conserved, except for a 1.4-kb glpTQ intergenic region that was found in most Hib strains. The presence of this intergenic region results in divergent glpTQ transcriptional profiles for Hib and NTHi where Hib strains appear to have evolved an alternative promoter for glpQ expression. Based on the intergenic region's low G+C content, we speculate that this DNA fragment was acquired by lateral transfer.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/141868
- author
- Song, Xin-Ming and Janson, Håkan LU
- organization
- publishing date
- 2003
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Bacteriology
- volume
- 185
- issue
- 24
- pages
- 7285 - 7290
- publisher
- American Society for Microbiology
- external identifiers
-
- pmid:14645291
- wos:000187183300031
- scopus:0345529060
- ISSN
- 0021-9193
- DOI
- 10.1128/JB.185.24.7285-7290.2003
- language
- English
- LU publication?
- yes
- id
- b73ab4bd-aaf4-44f2-9784-12bc7f038356 (old id 141868)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14645291&query_hl=37
- date added to LUP
- 2016-04-01 11:39:50
- date last changed
- 2022-01-26 08:22:29
@article{b73ab4bd-aaf4-44f2-9784-12bc7f038356, abstract = {{The glpTQ operon of Haemophilus influenzae type b (Hib) and nontypeable H. influenzae (NTHi) strains is highly conserved, except for a 1.4-kb glpTQ intergenic region that was found in most Hib strains. The presence of this intergenic region results in divergent glpTQ transcriptional profiles for Hib and NTHi where Hib strains appear to have evolved an alternative promoter for glpQ expression. Based on the intergenic region's low G+C content, we speculate that this DNA fragment was acquired by lateral transfer.}}, author = {{Song, Xin-Ming and Janson, Håkan}}, issn = {{0021-9193}}, language = {{eng}}, number = {{24}}, pages = {{7285--7290}}, publisher = {{American Society for Microbiology}}, series = {{Journal of Bacteriology}}, title = {{Differences in genetic and transcriptional organization of the glpTQ operons between Haemophilus influenzae type b and nontypeable strains}}, url = {{https://lup.lub.lu.se/search/files/2584497/624791.pdf}}, doi = {{10.1128/JB.185.24.7285-7290.2003}}, volume = {{185}}, year = {{2003}}, }