Bleeding peptic ulcer - time trends in incidence, treatment and mortality in Sweden.
(2009) In Alimentary pharmacology & therapeutics 30. p.392-398- Abstract
- Abstract Background: The incidence of peptic ulcer disease was expected to decrease following the introduction of acid inhibitors and H. pylori eradication. Aim: This study analyses possible changes in the incidence of bleeding peptic ulcer, treatment and mortality over time. Methods: Residents of Malmö hospitalised for bleeding gastric or duodenal ulcer disease1987-2004 were identified in hospital databases (n=1610). The material was divided in 6-year periods in order to identify changes over time. All patients who had been submitted to emergency surgery (n=137) were reviewed. Results: The incidence rate for bleeding gastric or duodenal ulcers decreased by one half in males and by one third in females and emergency operations decreased... (More)
- Abstract Background: The incidence of peptic ulcer disease was expected to decrease following the introduction of acid inhibitors and H. pylori eradication. Aim: This study analyses possible changes in the incidence of bleeding peptic ulcer, treatment and mortality over time. Methods: Residents of Malmö hospitalised for bleeding gastric or duodenal ulcer disease1987-2004 were identified in hospital databases (n=1610). The material was divided in 6-year periods in order to identify changes over time. All patients who had been submitted to emergency surgery (n=137) were reviewed. Results: The incidence rate for bleeding gastric or duodenal ulcers decreased by one half in males and by one third in females and emergency operations decreased significantly (9.2, 7.5 and 5.7% during the three time periods respectively (p<0.05). The postoperative mortality tended to decrease (9.7, 2.4 and 3.7% respectively) and the 30-day mortality rates in the whole material were 1.2, 3.6 and 3.4% during the different time periods. Conclusion: The incidence of bleeding gastric and duodenal ulcer disease has decreased markedly. Operative treatment has been replaced by endoscopic treatment. The bleeding ulcer related mortality was less than 4% and has not changed over time. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1434377
- author
- Sadic, Jalal LU ; Borgström, Anders LU ; Manjer, Jonas LU ; Toth, Ervin LU and Lindell, Gert LU
- organization
- publishing date
- 2009
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Alimentary pharmacology & therapeutics
- volume
- 30
- pages
- 392 - 398
- publisher
- Wiley-Blackwell
- external identifiers
-
- wos:000268166300008
- pmid:19508403
- scopus:67651162335
- pmid:19508403
- ISSN
- 1365-2036
- DOI
- 10.1111/j.1365-2036.2009.04058.x
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Surgery Research Unit (013242220), Surgery (Lund) (013009000), Emergency medicine/Medicine/Surgery (013240200)
- id
- 679db63a-c438-424b-987c-539b89b2a856 (old id 1434377)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/19508403?dopt=Abstract
- date added to LUP
- 2016-04-04 09:31:05
- date last changed
- 2022-02-06 03:23:28
@article{679db63a-c438-424b-987c-539b89b2a856,
abstract = {{Abstract Background: The incidence of peptic ulcer disease was expected to decrease following the introduction of acid inhibitors and H. pylori eradication. Aim: This study analyses possible changes in the incidence of bleeding peptic ulcer, treatment and mortality over time. Methods: Residents of Malmö hospitalised for bleeding gastric or duodenal ulcer disease1987-2004 were identified in hospital databases (n=1610). The material was divided in 6-year periods in order to identify changes over time. All patients who had been submitted to emergency surgery (n=137) were reviewed. Results: The incidence rate for bleeding gastric or duodenal ulcers decreased by one half in males and by one third in females and emergency operations decreased significantly (9.2, 7.5 and 5.7% during the three time periods respectively (p<0.05). The postoperative mortality tended to decrease (9.7, 2.4 and 3.7% respectively) and the 30-day mortality rates in the whole material were 1.2, 3.6 and 3.4% during the different time periods. Conclusion: The incidence of bleeding gastric and duodenal ulcer disease has decreased markedly. Operative treatment has been replaced by endoscopic treatment. The bleeding ulcer related mortality was less than 4% and has not changed over time.}},
author = {{Sadic, Jalal and Borgström, Anders and Manjer, Jonas and Toth, Ervin and Lindell, Gert}},
issn = {{1365-2036}},
language = {{eng}},
pages = {{392--398}},
publisher = {{Wiley-Blackwell}},
series = {{Alimentary pharmacology & therapeutics}},
title = {{Bleeding peptic ulcer - time trends in incidence, treatment and mortality in Sweden.}},
url = {{http://dx.doi.org/10.1111/j.1365-2036.2009.04058.x}},
doi = {{10.1111/j.1365-2036.2009.04058.x}},
volume = {{30}},
year = {{2009}},
}