Epicardial and endocardial dispersion of ventricular repolarization. A study of monophasic action potential mapping in healthy pigs.
(2005) In Scandinavian Cardiovascular Journal 39(6). p.342-347- Abstract
- Objectives. To investigate the total dispersion of ventricular repolarization of the epi- and endocardium. Design. Monophasic action potentials (MAP) were recorded from 211 +/- 54 (151-353) left and right ventricular epi- and endocardial sites during atrial pacing in 10 pigs using the CARTO system. The activation time (AT), MAP duration (MAPd) and end of repolarization time (EOR) were measured. Results. The total dispersion of AT, EOR and MAPd, defined as the maximal differences of these parameters over both the epi- and endocardium, were 57 +/- 10, 84 +/- 20, and 75 +/- 21 ms respectively and were significantly larger than the respective epi- and endocardial dispersions (p < 0.05). The epicardial dispersion of AT, EOR and MAPd of both... (More)
- Objectives. To investigate the total dispersion of ventricular repolarization of the epi- and endocardium. Design. Monophasic action potentials (MAP) were recorded from 211 +/- 54 (151-353) left and right ventricular epi- and endocardial sites during atrial pacing in 10 pigs using the CARTO system. The activation time (AT), MAP duration (MAPd) and end of repolarization time (EOR) were measured. Results. The total dispersion of AT, EOR and MAPd, defined as the maximal differences of these parameters over both the epi- and endocardium, were 57 +/- 10, 84 +/- 20, and 75 +/- 21 ms respectively and were significantly larger than the respective epi- and endocardial dispersions (p < 0.05). The epicardial dispersion of AT, EOR and MAPd of both the right and left ventricles were significantly larger than that of each ventricle alone (p < 0.02). Sternotomy did not affect these dispersion parameters. Conclusion. Detailed mapping of epicardial repolarization in vivo using the MAP mapping technique is feasible. Both the epi- and endocardium of the two ventricles contribute significantly to the total dispersion of repolarization. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/148713
- author
- Kongstad Rasmussen, Ole LU ; Xia, Yunlong LU ; Liang, Yanchun ; Hertervig, Eva LU ; Ljungstrom, Erik ; Olsson, Bertil LU and Yuan, Shiwen LU
- organization
- publishing date
- 2005
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Repolarization, endocardium, epicardium, dispersion, MAP mapping
- in
- Scandinavian Cardiovascular Journal
- volume
- 39
- issue
- 6
- pages
- 342 - 347
- publisher
- Taylor & Francis
- external identifiers
-
- pmid:16352486
- wos:000234092300004
- scopus:31344472214
- ISSN
- 1651-2006
- DOI
- 10.1080/14017430500188744
- language
- English
- LU publication?
- yes
- id
- bfc6fd09-9f2d-4c2b-b31e-4748268f4927 (old id 148713)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16352486&dopt=Abstract
- date added to LUP
- 2016-04-01 16:34:04
- date last changed
- 2022-01-28 20:34:06
@article{bfc6fd09-9f2d-4c2b-b31e-4748268f4927, abstract = {{Objectives. To investigate the total dispersion of ventricular repolarization of the epi- and endocardium. Design. Monophasic action potentials (MAP) were recorded from 211 +/- 54 (151-353) left and right ventricular epi- and endocardial sites during atrial pacing in 10 pigs using the CARTO system. The activation time (AT), MAP duration (MAPd) and end of repolarization time (EOR) were measured. Results. The total dispersion of AT, EOR and MAPd, defined as the maximal differences of these parameters over both the epi- and endocardium, were 57 +/- 10, 84 +/- 20, and 75 +/- 21 ms respectively and were significantly larger than the respective epi- and endocardial dispersions (p < 0.05). The epicardial dispersion of AT, EOR and MAPd of both the right and left ventricles were significantly larger than that of each ventricle alone (p < 0.02). Sternotomy did not affect these dispersion parameters. Conclusion. Detailed mapping of epicardial repolarization in vivo using the MAP mapping technique is feasible. Both the epi- and endocardium of the two ventricles contribute significantly to the total dispersion of repolarization.}}, author = {{Kongstad Rasmussen, Ole and Xia, Yunlong and Liang, Yanchun and Hertervig, Eva and Ljungstrom, Erik and Olsson, Bertil and Yuan, Shiwen}}, issn = {{1651-2006}}, keywords = {{Repolarization; endocardium; epicardium; dispersion; MAP mapping}}, language = {{eng}}, number = {{6}}, pages = {{342--347}}, publisher = {{Taylor & Francis}}, series = {{Scandinavian Cardiovascular Journal}}, title = {{Epicardial and endocardial dispersion of ventricular repolarization. A study of monophasic action potential mapping in healthy pigs.}}, url = {{http://dx.doi.org/10.1080/14017430500188744}}, doi = {{10.1080/14017430500188744}}, volume = {{39}}, year = {{2005}}, }