Pulmonary Embolism Associated With Protein C Deficiency and Abuse of Anabolic-androgen Steroids
(2010) In Clinical and Applied Thrombosis/Hemostasis 16(2). p.228-231- Abstract
- We present the case of a 19-year-old male athlete with protein C deficiency who developed proximal deep venous thrombosis and pulmonary embolism while abusing anabolic-androgenic steroids. Anabolic-androgenic steroids have been reported to have anticoagulatory and profibrinolytic effects in patients with protein C deficiency. Despite these antithrombotic effects, the patient developed repeated venous thromboembolism during treatment with low-molecular-weight heparin. The net effect of anabolic-androgenic steroids on the haemostatic system may change from antithrombotic to prothrombotic in male abusers of anabolic steroids with protein C deficiency.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1588099
- author
- Alhadad, Alaa LU ; Acosta, Stefan LU ; Sarabi, Latif and Kölbel, Tilo LU
- organization
- publishing date
- 2010
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Clinical and Applied Thrombosis/Hemostasis
- volume
- 16
- issue
- 2
- pages
- 228 - 231
- publisher
- SAGE Publications
- external identifiers
-
- wos:000275738500019
- scopus:77949876536
- pmid:18977778
- ISSN
- 1938-2723
- DOI
- 10.1177/1076029608324930
- language
- English
- LU publication?
- yes
- id
- 23f18d70-d799-4c82-b1fe-4ee419966642 (old id 1588099)
- date added to LUP
- 2016-04-01 11:14:06
- date last changed
- 2022-01-26 06:24:22
@article{23f18d70-d799-4c82-b1fe-4ee419966642, abstract = {{We present the case of a 19-year-old male athlete with protein C deficiency who developed proximal deep venous thrombosis and pulmonary embolism while abusing anabolic-androgenic steroids. Anabolic-androgenic steroids have been reported to have anticoagulatory and profibrinolytic effects in patients with protein C deficiency. Despite these antithrombotic effects, the patient developed repeated venous thromboembolism during treatment with low-molecular-weight heparin. The net effect of anabolic-androgenic steroids on the haemostatic system may change from antithrombotic to prothrombotic in male abusers of anabolic steroids with protein C deficiency.}}, author = {{Alhadad, Alaa and Acosta, Stefan and Sarabi, Latif and Kölbel, Tilo}}, issn = {{1938-2723}}, language = {{eng}}, number = {{2}}, pages = {{228--231}}, publisher = {{SAGE Publications}}, series = {{Clinical and Applied Thrombosis/Hemostasis}}, title = {{Pulmonary Embolism Associated With Protein C Deficiency and Abuse of Anabolic-androgen Steroids}}, url = {{http://dx.doi.org/10.1177/1076029608324930}}, doi = {{10.1177/1076029608324930}}, volume = {{16}}, year = {{2010}}, }