Plasmodium motility : actin not actin' like actin
Schüler, Herwig LU
and Matuschewski, Kai
(2006)
In Trends in Parasitology
22(4).
p.7-146
- Abstract
Apicomplexan parasites such as Plasmodium and Toxoplasma display actomyosin-dependent motility in the absence of readily detectable actin polymers. Three recent studies indicate that parasite actin polymers, either harvested from parasites or formed from purified recombinant proteins, are exceptionally short ( approximately 100 nm). We propose that parasite motility could be directed by the transient formation of short actin filament scaffolds. Parasite actin polymers that support transmembrane receptors are pulled, by myosin interaction, backwards along the parasite periphery, resulting in forward movement.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/170b2d34-8600-47b3-b12d-adeba182f397
- author
- Schüler, Herwig
LU
and Matuschewski, Kai
- publishing date
- 2006-04
- type
- Contribution to journal
- publication status
- published
- keywords
- Actin Cytoskeleton/chemistry, Actins/chemistry, Actomyosin/physiology, Animals, Movement/physiology, Plasmodium/chemistry
- in
- Trends in Parasitology
- volume
- 22
- issue
- 4
- pages
- 2 pages
- publisher
- Elsevier
- external identifiers
-
- pmid:16500149
- scopus:33645072710
- ISSN
- 1471-4922
- DOI
- 10.1016/j.pt.2006.02.005
- language
- English
- LU publication?
- no
- id
- 170b2d34-8600-47b3-b12d-adeba182f397
- date added to LUP
- 2024-11-21 18:06:14
- date last changed
- 2025-01-17 03:12:47
@article{170b2d34-8600-47b3-b12d-adeba182f397,
abstract = {{<p>Apicomplexan parasites such as Plasmodium and Toxoplasma display actomyosin-dependent motility in the absence of readily detectable actin polymers. Three recent studies indicate that parasite actin polymers, either harvested from parasites or formed from purified recombinant proteins, are exceptionally short ( approximately 100 nm). We propose that parasite motility could be directed by the transient formation of short actin filament scaffolds. Parasite actin polymers that support transmembrane receptors are pulled, by myosin interaction, backwards along the parasite periphery, resulting in forward movement.</p>}},
author = {{Schüler, Herwig and Matuschewski, Kai}},
issn = {{1471-4922}},
keywords = {{Actin Cytoskeleton/chemistry; Actins/chemistry; Actomyosin/physiology; Animals; Movement/physiology; Plasmodium/chemistry}},
language = {{eng}},
number = {{4}},
pages = {{7--146}},
publisher = {{Elsevier}},
series = {{Trends in Parasitology}},
title = {{<i>Plasmodium </i>motility : actin not actin' like actin}},
url = {{http://dx.doi.org/10.1016/j.pt.2006.02.005}},
doi = {{10.1016/j.pt.2006.02.005}},
volume = {{22}},
year = {{2006}},
}