Development of an Electrochemical Meta-Ion Biosensor Using Self-Assembled Peptide Nanofibrils
(2011) In ACS Applied Materials and Interfaces 3(5). p.1594-1600- Abstract
- This article describes the combination of self-assembled peptide nanofibrils with metal electrodes for the development of an electrochemical metal-ion biosensor. The biological nanofibrils were immobilized on gold electrodes and used as biorecognition elements for the complexation with copper ions. These nanofibrils were obtained under aqueous conditions, at room temperature and outside the clean room. The functionalized gold electrode was evaluated by cyclic voltammetry, impedance spectroscopy, energy dispersive X-ray and atomic force microscopy. The obtained results displayed a layer of nanofibrils able to complex with copper ions in solution. The response of the obtained biosensor was linear up to 50 mu M copper and presented a... (More)
- This article describes the combination of self-assembled peptide nanofibrils with metal electrodes for the development of an electrochemical metal-ion biosensor. The biological nanofibrils were immobilized on gold electrodes and used as biorecognition elements for the complexation with copper ions. These nanofibrils were obtained under aqueous conditions, at room temperature and outside the clean room. The functionalized gold electrode was evaluated by cyclic voltammetry, impedance spectroscopy, energy dispersive X-ray and atomic force microscopy. The obtained results displayed a layer of nanofibrils able to complex with copper ions in solution. The response of the obtained biosensor was linear up to 50 mu M copper and presented a sensitivity of 0.68 mu A cm(-2) mu M-1. Moreover, the fabricated sensor could be regenerated to a copper-free state allowing its reutilization. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1986612
- author
- Bruno, Viguier LU ; Zor, Kinga LU ; Kasotakis, Emmanouil ; Mitraki, Anna ; Clausen, Casper H. ; Svendsen, Winnie E. and Castillo-Leon, Jaime
- organization
- publishing date
- 2011
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- self-assembly, peptide, nanofibrils, electrochemical biosensor, copper, biomaterial
- in
- ACS Applied Materials and Interfaces
- volume
- 3
- issue
- 5
- pages
- 1594 - 1600
- publisher
- The American Chemical Society (ACS)
- external identifiers
-
- wos:000290843800032
- scopus:80051694801
- pmid:21443268
- ISSN
- 1944-8244
- DOI
- 10.1021/am200149h
- language
- English
- LU publication?
- yes
- id
- 551abf39-899f-4a2b-a9a2-080abdce9652 (old id 1986612)
- date added to LUP
- 2016-04-01 10:26:35
- date last changed
- 2022-04-12 06:17:06
@article{551abf39-899f-4a2b-a9a2-080abdce9652, abstract = {{This article describes the combination of self-assembled peptide nanofibrils with metal electrodes for the development of an electrochemical metal-ion biosensor. The biological nanofibrils were immobilized on gold electrodes and used as biorecognition elements for the complexation with copper ions. These nanofibrils were obtained under aqueous conditions, at room temperature and outside the clean room. The functionalized gold electrode was evaluated by cyclic voltammetry, impedance spectroscopy, energy dispersive X-ray and atomic force microscopy. The obtained results displayed a layer of nanofibrils able to complex with copper ions in solution. The response of the obtained biosensor was linear up to 50 mu M copper and presented a sensitivity of 0.68 mu A cm(-2) mu M-1. Moreover, the fabricated sensor could be regenerated to a copper-free state allowing its reutilization.}}, author = {{Bruno, Viguier and Zor, Kinga and Kasotakis, Emmanouil and Mitraki, Anna and Clausen, Casper H. and Svendsen, Winnie E. and Castillo-Leon, Jaime}}, issn = {{1944-8244}}, keywords = {{self-assembly; peptide; nanofibrils; electrochemical biosensor; copper; biomaterial}}, language = {{eng}}, number = {{5}}, pages = {{1594--1600}}, publisher = {{The American Chemical Society (ACS)}}, series = {{ACS Applied Materials and Interfaces}}, title = {{Development of an Electrochemical Meta-Ion Biosensor Using Self-Assembled Peptide Nanofibrils}}, url = {{http://dx.doi.org/10.1021/am200149h}}, doi = {{10.1021/am200149h}}, volume = {{3}}, year = {{2011}}, }