A mixed endocrine adrenal tumour causing steatorrhoea
(1987) In Gut 28(10). p.301-1298- Abstract
A 60 year old man developed steatorrhoea, weight loss, mild diabetes mellitus, labile hypertension and limb cramps. Raised plasma concentrations of catecholamines, particularly noradrenaline and a computed tomography-scan showing an adrenal tumour strongly suggested a pheochromocytoma. Adrenoreceptor blockade reversed the symptoms, decreased faecal fat, and increased duodenal trypsin to normal concentrations. After adrenalectomy the patient was asymptomatic and there was no steatorrhoea. The blood glucose concentrations became normal. Immunocytochemistry revealed the tumour cells to store large amounts of enkephalin and somatostatin reactive material and moderate amounts of immunoreactive beta-endorphin and dynorphin.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1a7347bd-a484-45b4-b72d-d7ec3061d066
- author
- Thesleff, P ; Benoni, C LU ; Mårtensson, H ; Nilsson, A LU ; Sundler, F and Akesson, B LU
- organization
- publishing date
- 1987-10
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Adrenal Gland Neoplasms/complications, Celiac Disease/etiology, Endorphins/metabolism, Humans, Male, Middle Aged, Norepinephrine/metabolism, Pheochromocytoma/complications, Somatostatin/metabolism
- in
- Gut
- volume
- 28
- issue
- 10
- pages
- 4 pages
- publisher
- BMJ Publishing Group
- external identifiers
-
- scopus:0023232158
- pmid:2890560
- ISSN
- 0017-5749
- DOI
- 10.1136/gut.28.10.1298
- language
- English
- LU publication?
- yes
- id
- 1a7347bd-a484-45b4-b72d-d7ec3061d066
- date added to LUP
- 2019-09-24 15:10:48
- date last changed
- 2024-01-01 21:10:37
@article{1a7347bd-a484-45b4-b72d-d7ec3061d066, abstract = {{<p>A 60 year old man developed steatorrhoea, weight loss, mild diabetes mellitus, labile hypertension and limb cramps. Raised plasma concentrations of catecholamines, particularly noradrenaline and a computed tomography-scan showing an adrenal tumour strongly suggested a pheochromocytoma. Adrenoreceptor blockade reversed the symptoms, decreased faecal fat, and increased duodenal trypsin to normal concentrations. After adrenalectomy the patient was asymptomatic and there was no steatorrhoea. The blood glucose concentrations became normal. Immunocytochemistry revealed the tumour cells to store large amounts of enkephalin and somatostatin reactive material and moderate amounts of immunoreactive beta-endorphin and dynorphin.</p>}}, author = {{Thesleff, P and Benoni, C and Mårtensson, H and Nilsson, A and Sundler, F and Akesson, B}}, issn = {{0017-5749}}, keywords = {{Adrenal Gland Neoplasms/complications; Celiac Disease/etiology; Endorphins/metabolism; Humans; Male; Middle Aged; Norepinephrine/metabolism; Pheochromocytoma/complications; Somatostatin/metabolism}}, language = {{eng}}, number = {{10}}, pages = {{301--1298}}, publisher = {{BMJ Publishing Group}}, series = {{Gut}}, title = {{A mixed endocrine adrenal tumour causing steatorrhoea}}, url = {{http://dx.doi.org/10.1136/gut.28.10.1298}}, doi = {{10.1136/gut.28.10.1298}}, volume = {{28}}, year = {{1987}}, }