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Bowel dysfunction following nerve-sparing radical hysterectomy for cervical cancer : A prospective study

Loizzi, V. ; Cormio, G. ; Lobascio, P. L. ; Marino, F. ; De Fazio, M. ; Falagario, M. LU orcid ; Leone, L. ; Difiore, G. ; Scardigno, D. and Selvaggi, L. , et al. (2014) In Oncology (Switzerland) 86(4). p.239-243
Abstract

Objective: To objectively assess anorectal dysfunction following nerve-sparing radical hysterectomy in stage I-II cervical carcinoma patients. Material and Methods: Between 2008 and 2012, 21 patients with primary cervical cancer stage FIGO I-II were enrolled in this prospective study. All women underwent nerve-sparing radical hysterectomy. Anorectal manometry was performed preoperatively and 6 months after surgery. A paired Student t test was used to assess the statistical difference between the manometric evaluations. A p value <0.05 was considered statistically significant. Results: Twenty-one patients were available for follow-up. Maximal and mean anal resting and squeezing pressures were unaffected by the surgical procedure,... (More)

Objective: To objectively assess anorectal dysfunction following nerve-sparing radical hysterectomy in stage I-II cervical carcinoma patients. Material and Methods: Between 2008 and 2012, 21 patients with primary cervical cancer stage FIGO I-II were enrolled in this prospective study. All women underwent nerve-sparing radical hysterectomy. Anorectal manometry was performed preoperatively and 6 months after surgery. A paired Student t test was used to assess the statistical difference between the manometric evaluations. A p value <0.05 was considered statistically significant. Results: Twenty-one patients were available for follow-up. Maximal and mean anal resting and squeezing pressures were unaffected by the surgical procedure, rectoanal inhibitory reflex and length of the high anal pressure zone did not change after the operation. The minimal volume to elicit rectal sensation, urge to defecate and maximal tolerable volume did not change significantly in the postoperative period, although they decreased in 2 and increased in 3 patients. In addition, rectal compliance did not change after surgery. Furthermore, no significant differences were found between patients who were or were not treated with adjuvant radiotherapy. Conclusions: Our findings suggest that nerve-sparing radical hysterectomy for cervical cancer does not seem to be associated with long-term anorectal dysfunction.

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publishing date
type
Contribution to journal
publication status
published
subject
keywords
Bowel dysfunction, Cervical cancer, Nerve-sparing radical hysterectomy
in
Oncology (Switzerland)
volume
86
issue
4
pages
239 - 243
publisher
Karger
external identifiers
  • pmid:24902494
  • scopus:84901732334
ISSN
0030-2414
DOI
10.1159/000362213
language
English
LU publication?
no
id
1fb70336-ea2a-4792-99b3-c2f05786c7e3
date added to LUP
2019-02-16 08:33:05
date last changed
2024-01-15 14:41:10
@article{1fb70336-ea2a-4792-99b3-c2f05786c7e3,
  abstract     = {{<p>Objective: To objectively assess anorectal dysfunction following nerve-sparing radical hysterectomy in stage I-II cervical carcinoma patients. Material and Methods: Between 2008 and 2012, 21 patients with primary cervical cancer stage FIGO I-II were enrolled in this prospective study. All women underwent nerve-sparing radical hysterectomy. Anorectal manometry was performed preoperatively and 6 months after surgery. A paired Student t test was used to assess the statistical difference between the manometric evaluations. A p value &lt;0.05 was considered statistically significant. Results: Twenty-one patients were available for follow-up. Maximal and mean anal resting and squeezing pressures were unaffected by the surgical procedure, rectoanal inhibitory reflex and length of the high anal pressure zone did not change after the operation. The minimal volume to elicit rectal sensation, urge to defecate and maximal tolerable volume did not change significantly in the postoperative period, although they decreased in 2 and increased in 3 patients. In addition, rectal compliance did not change after surgery. Furthermore, no significant differences were found between patients who were or were not treated with adjuvant radiotherapy. Conclusions: Our findings suggest that nerve-sparing radical hysterectomy for cervical cancer does not seem to be associated with long-term anorectal dysfunction.</p>}},
  author       = {{Loizzi, V. and Cormio, G. and Lobascio, P. L. and Marino, F. and De Fazio, M. and Falagario, M. and Leone, L. and Difiore, G. and Scardigno, D. and Selvaggi, L. and Altomare, D. F.}},
  issn         = {{0030-2414}},
  keywords     = {{Bowel dysfunction; Cervical cancer; Nerve-sparing radical hysterectomy}},
  language     = {{eng}},
  month        = {{01}},
  number       = {{4}},
  pages        = {{239--243}},
  publisher    = {{Karger}},
  series       = {{Oncology (Switzerland)}},
  title        = {{Bowel dysfunction following nerve-sparing radical hysterectomy for cervical cancer : A prospective study}},
  url          = {{http://dx.doi.org/10.1159/000362213}},
  doi          = {{10.1159/000362213}},
  volume       = {{86}},
  year         = {{2014}},
}