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Effects of B(1) inhomogeneity correction for three-dimensional variable flip angle T(1) measurements in hip dGEMRIC at 3 T and 1.5 T.

Siversson, Carl LU ; Chan, Jenny ; Tiderius, Carl Johan LU ; Mamisch, Tallal Charles ; Jellus, Vladimir ; Svensson, Jonas LU and Kim, Young-Jo (2012) In Magnetic Resonance in Medicine 67(6). p.1776-1781
Abstract
Delayed gadolinium-enhanced MRI of cartilage is a technique for studying the development of osteoarthritis using quantitative T(1) measurements. Three-dimensional variable flip angle is a promising method for performing such measurements rapidly, by using two successive spoiled gradient echo sequences with different excitation pulse flip angles. However, the three-dimensional variable flip angle method is very sensitive to inhomogeneities in the transmitted B(1) field in vivo. In this study, a method for correcting for such inhomogeneities, using an additional B(1) mapping spin-echo sequence, was evaluated. Phantom studies concluded that three-dimensional variable flip angle with B(1) correction calculates accurate T(1) values also in... (More)
Delayed gadolinium-enhanced MRI of cartilage is a technique for studying the development of osteoarthritis using quantitative T(1) measurements. Three-dimensional variable flip angle is a promising method for performing such measurements rapidly, by using two successive spoiled gradient echo sequences with different excitation pulse flip angles. However, the three-dimensional variable flip angle method is very sensitive to inhomogeneities in the transmitted B(1) field in vivo. In this study, a method for correcting for such inhomogeneities, using an additional B(1) mapping spin-echo sequence, was evaluated. Phantom studies concluded that three-dimensional variable flip angle with B(1) correction calculates accurate T(1) values also in areas with high B(1) deviation. Retrospective analysis of in vivo hip delayed gadolinium-enhanced MRI of cartilage data from 40 subjects showed the difference between three-dimensional variable flip angle with and without B(1) correction to be generally two to three times higher at 3 T than at 1.5 T. In conclusion, the B(1) variations should always be taken into account, both at 1.5 T and at 3 T. Magn Reson Med, 2011. © 2011 Wiley-Liss, Inc. (Less)
Please use this url to cite or link to this publication:
author
; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
B1 correction, T1 mapping, dGEMRIC, cartilage
in
Magnetic Resonance in Medicine
volume
67
issue
6
pages
1776 - 1781
publisher
John Wiley & Sons Inc.
external identifiers
  • wos:000304086000030
  • pmid:22135218
  • scopus:84861226958
  • pmid:22135218
ISSN
1522-2594
DOI
10.1002/mrm.23150
language
English
LU publication?
yes
id
9069351d-c352-4c03-8cc4-dd340f987de2 (old id 2274657)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/22135218?dopt=Abstract
date added to LUP
2016-04-01 10:13:16
date last changed
2022-01-25 20:59:36
@article{9069351d-c352-4c03-8cc4-dd340f987de2,
  abstract     = {{Delayed gadolinium-enhanced MRI of cartilage is a technique for studying the development of osteoarthritis using quantitative T(1) measurements. Three-dimensional variable flip angle is a promising method for performing such measurements rapidly, by using two successive spoiled gradient echo sequences with different excitation pulse flip angles. However, the three-dimensional variable flip angle method is very sensitive to inhomogeneities in the transmitted B(1) field in vivo. In this study, a method for correcting for such inhomogeneities, using an additional B(1) mapping spin-echo sequence, was evaluated. Phantom studies concluded that three-dimensional variable flip angle with B(1) correction calculates accurate T(1) values also in areas with high B(1) deviation. Retrospective analysis of in vivo hip delayed gadolinium-enhanced MRI of cartilage data from 40 subjects showed the difference between three-dimensional variable flip angle with and without B(1) correction to be generally two to three times higher at 3 T than at 1.5 T. In conclusion, the B(1) variations should always be taken into account, both at 1.5 T and at 3 T. Magn Reson Med, 2011. © 2011 Wiley-Liss, Inc.}},
  author       = {{Siversson, Carl and Chan, Jenny and Tiderius, Carl Johan and Mamisch, Tallal Charles and Jellus, Vladimir and Svensson, Jonas and Kim, Young-Jo}},
  issn         = {{1522-2594}},
  keywords     = {{B1 correction; T1 mapping; dGEMRIC; cartilage}},
  language     = {{eng}},
  number       = {{6}},
  pages        = {{1776--1781}},
  publisher    = {{John Wiley & Sons Inc.}},
  series       = {{Magnetic Resonance in Medicine}},
  title        = {{Effects of B(1) inhomogeneity correction for three-dimensional variable flip angle T(1) measurements in hip dGEMRIC at 3 T and 1.5 T.}},
  url          = {{http://dx.doi.org/10.1002/mrm.23150}},
  doi          = {{10.1002/mrm.23150}},
  volume       = {{67}},
  year         = {{2012}},
}