Comparative safety and efficacy of new-generation single-layer polytetrafluorethylene- versus polyurethane-covered stents in patients with coronary artery perforation for the RECOVER (REsults after percutaneous interventions with COVERed stents) Investigators
(2025) In Cardiovascular Intervention and Therapeutics 40(2). p.296-305- Abstract
New-generation single-layer polytetrafluorethylene (PTFE-) or polyurethane (PU-) covered stent (CS) for the treatment of coronary artery perforation (CAP) during PCI offer high procedural efficacy. To evaluate the comparative long-term safety and efficacy of both devices. This is a multicenter pooled analysis of individual data of patients with CAP undergoing implantation of single-layer PTFE-CS or PU-CS. Procedural endpoint was strategy success defined as successful placement of CS and sealing of perforation without surgical conversion. Clinical endpoints were mortality, myocardial infarction (MI), target vessel revascularization (TVR) and definite or probable stent thrombosis (def/prob ST) at 12 months. Seventy patients with CAP... (More)
New-generation single-layer polytetrafluorethylene (PTFE-) or polyurethane (PU-) covered stent (CS) for the treatment of coronary artery perforation (CAP) during PCI offer high procedural efficacy. To evaluate the comparative long-term safety and efficacy of both devices. This is a multicenter pooled analysis of individual data of patients with CAP undergoing implantation of single-layer PTFE-CS or PU-CS. Procedural endpoint was strategy success defined as successful placement of CS and sealing of perforation without surgical conversion. Clinical endpoints were mortality, myocardial infarction (MI), target vessel revascularization (TVR) and definite or probable stent thrombosis (def/prob ST) at 12 months. Seventy patients with CAP underwent implantation of two hundred eight CS, ninety-two PTFE-CS, and one hundred sixteen PU-CS. More than 1 stent was implanted in 13 patients (17.1%) in PTFE-CS group and 19 patients (20.2%) in PU-CS group, P = 0.80. Strategy success was high (96.1% versus 92.5%., P = 0.62). At 12 months, 71 patients (93.2%) in PTFE-CS group versus 79 patients (81%) in the PU-CS were alive, P = 0.05; TVR occurred in 14 patients (28.4%) in PTFE-CS group and 12 patients (17.9%) in PU-CS group, P= 0.54; MI in 1 patient (1.3%) in PTFE-CS group and 1 patients (1.1%) in PU-CS group, P = 0.86. Rates of def/prob ST were comparable 1.3% in PTFE-CS versus 3.1% in PU-CS P = 0.95. A strategy of implantation of a new-generation single-layer PTFE- or PU-CS for the treatment of coronary artery perforation showed high success rates. Both new-generation CS showed favorable and similar clinical safety, in particular with regard to thrombotic events.
(Less)
- author
- organization
- publishing date
- 2025-04
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Coronary artery perforation, Covered stent, Polytetraflourethylene, Polyurethane
- in
- Cardiovascular Intervention and Therapeutics
- volume
- 40
- issue
- 2
- pages
- 10 pages
- publisher
- Springer
- external identifiers
-
- scopus:85217716531
- pmid:39918675
- ISSN
- 1868-4300
- DOI
- 10.1007/s12928-025-01084-y
- language
- English
- LU publication?
- yes
- id
- 2561bba3-d6e0-4573-8635-e3192e3d3374
- date added to LUP
- 2025-07-03 11:23:05
- date last changed
- 2025-07-17 12:13:30
@article{2561bba3-d6e0-4573-8635-e3192e3d3374,
abstract = {{<p>New-generation single-layer polytetrafluorethylene (PTFE-) or polyurethane (PU-) covered stent (CS) for the treatment of coronary artery perforation (CAP) during PCI offer high procedural efficacy. To evaluate the comparative long-term safety and efficacy of both devices. This is a multicenter pooled analysis of individual data of patients with CAP undergoing implantation of single-layer PTFE-CS or PU-CS. Procedural endpoint was strategy success defined as successful placement of CS and sealing of perforation without surgical conversion. Clinical endpoints were mortality, myocardial infarction (MI), target vessel revascularization (TVR) and definite or probable stent thrombosis (def/prob ST) at 12 months. Seventy patients with CAP underwent implantation of two hundred eight CS, ninety-two PTFE-CS, and one hundred sixteen PU-CS. More than 1 stent was implanted in 13 patients (17.1%) in PTFE-CS group and 19 patients (20.2%) in PU-CS group, P = 0.80. Strategy success was high (96.1% versus 92.5%., P = 0.62). At 12 months, 71 patients (93.2%) in PTFE-CS group versus 79 patients (81%) in the PU-CS were alive, P = 0.05; TVR occurred in 14 patients (28.4%) in PTFE-CS group and 12 patients (17.9%) in PU-CS group, P= 0.54; MI in 1 patient (1.3%) in PTFE-CS group and 1 patients (1.1%) in PU-CS group, P = 0.86. Rates of def/prob ST were comparable 1.3% in PTFE-CS versus 3.1% in PU-CS P = 0.95. A strategy of implantation of a new-generation single-layer PTFE- or PU-CS for the treatment of coronary artery perforation showed high success rates. Both new-generation CS showed favorable and similar clinical safety, in particular with regard to thrombotic events.</p>}},
author = {{Voll, Felix and Olivecronab, Göran and Ferenc, Miroslaw and Hellig, Farrel and Schlundt, Christian and Wöhrle, Jochen and Cassese, Salvatore and Rottbauer, Wolfgang and Witkowski, Adam and Xhepa, Erion and Kuliczkowski, Wiktor and Strauss, Lisa and Schrage, Benedikt and Joner, Michael and von zur Mühlen, Constantin and Cook, Stephane and Miljak, Tomislav and Eggebrecht, Holger and Eeckhout, Eric and Laugwitz, Karl Ludwig and Monsegu, Jacques and Schunkert, Heribert and Westermann, Dirk and Kastrati, Adnan and Dumonteil, Nicolas and Birkemeyer, Ralf and Kufner, Sebastian}},
issn = {{1868-4300}},
keywords = {{Coronary artery perforation; Covered stent; Polytetraflourethylene; Polyurethane}},
language = {{eng}},
number = {{2}},
pages = {{296--305}},
publisher = {{Springer}},
series = {{Cardiovascular Intervention and Therapeutics}},
title = {{Comparative safety and efficacy of new-generation single-layer polytetrafluorethylene- versus polyurethane-covered stents in patients with coronary artery perforation for the RECOVER (REsults after percutaneous interventions with COVERed stents) Investigators}},
url = {{http://dx.doi.org/10.1007/s12928-025-01084-y}},
doi = {{10.1007/s12928-025-01084-y}},
volume = {{40}},
year = {{2025}},
}