Familial Aggregation of Lymphoplasmacytic Lymphoma/Waldenstrom Macroglobulinemia with Solid Tumors and Myeloid Malignancies
(2012) In Acta Haematologica 127(3). p.173-177- Abstract
- Lymphoplasmacytic lymphoma (LPL)/Waldenstrom macroglobulinemia (WM) is a B-cell disorder resulting from the accumulation, predominantly in the bone marrow, of clonally related lymphoplasmacytic cells. LPL/WM is a very rare disease, with an incidence rate of 3-4 cases per million people per year. Currently, the causes of LPL/WM are poorly understood; however, there are emerging data to support a role for immune-related factors in the pathogenesis of LPL/WM. In addition, data show that genetic factors are of importance in the etiology of LPL/WM. In this paper, we will review the current knowledge about familiality of LPL/WM and provide novel data on solid tumors and myeloid malignancies in first-degree relatives of LPL/WM patients. Copyright... (More)
- Lymphoplasmacytic lymphoma (LPL)/Waldenstrom macroglobulinemia (WM) is a B-cell disorder resulting from the accumulation, predominantly in the bone marrow, of clonally related lymphoplasmacytic cells. LPL/WM is a very rare disease, with an incidence rate of 3-4 cases per million people per year. Currently, the causes of LPL/WM are poorly understood; however, there are emerging data to support a role for immune-related factors in the pathogenesis of LPL/WM. In addition, data show that genetic factors are of importance in the etiology of LPL/WM. In this paper, we will review the current knowledge about familiality of LPL/WM and provide novel data on solid tumors and myeloid malignancies in first-degree relatives of LPL/WM patients. Copyright (C) 2012 S. Karger AG, Basel (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2594577
- author
- Kristinsson, Sigurdur Y. ; Goldin, Lynn R. ; Turesson, Ingemar LU ; Bjorkholm, Magnus and Landgren, Ola
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Autoimmunity, Familial aggregation, Hematological malignancies, Lymphoplasmacytic lymphoma/Waldenstrom macroglobulinemia, Monoclonal, gammopathy of undetermined significance, Solid tumors, Susceptibility
- in
- Acta Haematologica
- volume
- 127
- issue
- 3
- pages
- 173 - 177
- publisher
- Karger
- external identifiers
-
- wos:000302205200009
- scopus:84856588322
- pmid:22310551
- ISSN
- 1421-9662
- DOI
- 10.1159/000335618
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Emergency medicine/Medicine/Surgery (013240200)
- id
- e57e243d-9ab3-4d9d-8fd0-ae6b5ed7fcda (old id 2594577)
- date added to LUP
- 2016-04-01 09:56:00
- date last changed
- 2022-04-27 08:57:45
@article{e57e243d-9ab3-4d9d-8fd0-ae6b5ed7fcda, abstract = {{Lymphoplasmacytic lymphoma (LPL)/Waldenstrom macroglobulinemia (WM) is a B-cell disorder resulting from the accumulation, predominantly in the bone marrow, of clonally related lymphoplasmacytic cells. LPL/WM is a very rare disease, with an incidence rate of 3-4 cases per million people per year. Currently, the causes of LPL/WM are poorly understood; however, there are emerging data to support a role for immune-related factors in the pathogenesis of LPL/WM. In addition, data show that genetic factors are of importance in the etiology of LPL/WM. In this paper, we will review the current knowledge about familiality of LPL/WM and provide novel data on solid tumors and myeloid malignancies in first-degree relatives of LPL/WM patients. Copyright (C) 2012 S. Karger AG, Basel}}, author = {{Kristinsson, Sigurdur Y. and Goldin, Lynn R. and Turesson, Ingemar and Bjorkholm, Magnus and Landgren, Ola}}, issn = {{1421-9662}}, keywords = {{Autoimmunity; Familial aggregation; Hematological malignancies; Lymphoplasmacytic lymphoma/Waldenstrom macroglobulinemia; Monoclonal; gammopathy of undetermined significance; Solid tumors; Susceptibility}}, language = {{eng}}, number = {{3}}, pages = {{173--177}}, publisher = {{Karger}}, series = {{Acta Haematologica}}, title = {{Familial Aggregation of Lymphoplasmacytic Lymphoma/Waldenstrom Macroglobulinemia with Solid Tumors and Myeloid Malignancies}}, url = {{https://lup.lub.lu.se/search/files/1401153/3128449.pdf}}, doi = {{10.1159/000335618}}, volume = {{127}}, year = {{2012}}, }