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PVC flooring is related to human uptake of phthalates in infants.

Carlstedt, Fredrik ; Jönsson, Bo A LU and Bornehag, Carl-Gustaf (2012) In Indoor Air
Abstract
Poly Vinyl Chloride (PVC) flooring material contains phthalates and it has been shown that such materials are important sources for phthalates in indoor dust. Phthalates are suspected endocrine disrupting chemicals (EDCs). Consecutive infants between two and six months old and their mothers were invited. A questionnaire about indoor environmental factors and family life style was used. Urinary metabolites of the phthalates di-ethyl phthalate (DEP), di-butyl phthalate (DBP), butylbenzyl phthalate (BBzP) and di-etylhexyl phthalate (DEHP) were measured in the urine of the children. Of 209 invited children, 110 (52%) participated. Urine samples were obtained from 83 of these. Urine levels of the BBzP metabolite monobenzyl phthalate (MBzP) was... (More)
Poly Vinyl Chloride (PVC) flooring material contains phthalates and it has been shown that such materials are important sources for phthalates in indoor dust. Phthalates are suspected endocrine disrupting chemicals (EDCs). Consecutive infants between two and six months old and their mothers were invited. A questionnaire about indoor environmental factors and family life style was used. Urinary metabolites of the phthalates di-ethyl phthalate (DEP), di-butyl phthalate (DBP), butylbenzyl phthalate (BBzP) and di-etylhexyl phthalate (DEHP) were measured in the urine of the children. Of 209 invited children, 110 (52%) participated. Urine samples were obtained from 83 of these. Urine levels of the BBzP metabolite monobenzyl phthalate (MBzP) was significantly higher in infants with PVC flooring in their bedrooms (p<0.007) and related to the body area of the infant. Levels of the DEHP metabolites MEHHP (p<0.01) and MEOHP (p<0.04) were higher in the two months old infants who were not exclusively breastfed when compared with breastfed children. The findings indicate that the use of soft PVC as flooring material may increase the human uptake of phthalates in infants. Urinary levels of phthalate metabolites during early life are associated to the use of PVC flooring in the bedroom, body area and the use of infant formula. © 2012 John Wiley & Sons A/S. (Less)
Please use this url to cite or link to this publication:
author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Indoor Air
publisher
Wiley-Blackwell
external identifiers
  • wos:000313594000005
  • pmid:22563949
  • scopus:84872372920
  • pmid:22563949
ISSN
0905-6947
DOI
10.1111/j.1600-0668.2012.00788.x
language
English
LU publication?
yes
id
5f18b23e-1f72-4951-a765-91b68033faba (old id 2609052)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/22563949?dopt=Abstract
date added to LUP
2016-04-04 09:22:29
date last changed
2022-04-08 02:42:44
@article{5f18b23e-1f72-4951-a765-91b68033faba,
  abstract     = {{Poly Vinyl Chloride (PVC) flooring material contains phthalates and it has been shown that such materials are important sources for phthalates in indoor dust. Phthalates are suspected endocrine disrupting chemicals (EDCs). Consecutive infants between two and six months old and their mothers were invited. A questionnaire about indoor environmental factors and family life style was used. Urinary metabolites of the phthalates di-ethyl phthalate (DEP), di-butyl phthalate (DBP), butylbenzyl phthalate (BBzP) and di-etylhexyl phthalate (DEHP) were measured in the urine of the children. Of 209 invited children, 110 (52%) participated. Urine samples were obtained from 83 of these. Urine levels of the BBzP metabolite monobenzyl phthalate (MBzP) was significantly higher in infants with PVC flooring in their bedrooms (p&lt;0.007) and related to the body area of the infant. Levels of the DEHP metabolites MEHHP (p&lt;0.01) and MEOHP (p&lt;0.04) were higher in the two months old infants who were not exclusively breastfed when compared with breastfed children. The findings indicate that the use of soft PVC as flooring material may increase the human uptake of phthalates in infants. Urinary levels of phthalate metabolites during early life are associated to the use of PVC flooring in the bedroom, body area and the use of infant formula. © 2012 John Wiley &amp; Sons A/S.}},
  author       = {{Carlstedt, Fredrik and Jönsson, Bo A and Bornehag, Carl-Gustaf}},
  issn         = {{0905-6947}},
  language     = {{eng}},
  month        = {{05}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Indoor Air}},
  title        = {{PVC flooring is related to human uptake of phthalates in infants.}},
  url          = {{http://dx.doi.org/10.1111/j.1600-0668.2012.00788.x}},
  doi          = {{10.1111/j.1600-0668.2012.00788.x}},
  year         = {{2012}},
}