Giant Cell Arteritis versus Takayasu Arteritis: An Update
(2020) In Mediterranean Journal of Rheumatology 31(2). p.174-182- Abstract
- Giant cell arteritis (GCA) and Takayasu Arteritis (TAK) are two systemic granulomatous vasculitides affecting medium- and large-sized arteries. Similarities in GCA and TAK regarding the clinical presentation, the systemic inflammatory response and the distribution of the arterial lesions, have triggered a debate over the last decade about whether GCA and TAK represent two different diseases, or are age-associated different clinical phenotypes of the same disease. On the other hand, there are differences regarding epidemiology, several clinical features (eg, polymyalgia rheumatica in GCA) and treatment. The aim of this review is to present the latest data regarding this question and to shed some light on the differences and similarities... (More)
- Giant cell arteritis (GCA) and Takayasu Arteritis (TAK) are two systemic granulomatous vasculitides affecting medium- and large-sized arteries. Similarities in GCA and TAK regarding the clinical presentation, the systemic inflammatory response and the distribution of the arterial lesions, have triggered a debate over the last decade about whether GCA and TAK represent two different diseases, or are age-associated different clinical phenotypes of the same disease. On the other hand, there are differences regarding epidemiology, several clinical features (eg, polymyalgia rheumatica in GCA) and treatment. The aim of this review is to present the latest data regarding this question and to shed some light on the differences and similarities between GCA and TAK regarding epidemiology, genetics, pathogenesis, histopathology, clinical presentation, imaging and treatment. The existing data in literature support the opinion that GCA and TAK are different clinical entities. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/28664f0c-2051-43f8-8162-716193905d59
- author
- Stamatis, Pavlos
LU
- organization
- publishing date
- 2020
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Mediterranean Journal of Rheumatology
- volume
- 31
- issue
- 2
- pages
- 174 - 182
- publisher
- Greek Rheumatology Society and Professional Association of Rheumatologists
- external identifiers
-
- pmid:32676554
- scopus:85106545562
- ISSN
- 2529-198X
- DOI
- 10.31138/mjr.31.2.174
- language
- English
- LU publication?
- yes
- id
- 28664f0c-2051-43f8-8162-716193905d59
- alternative location
- http://www.mjrheum.org/assets/files/792/file240_1158.pdf
- date added to LUP
- 2020-07-02 21:48:01
- date last changed
- 2022-04-18 23:15:20
@article{28664f0c-2051-43f8-8162-716193905d59, abstract = {{Giant cell arteritis (GCA) and Takayasu Arteritis (TAK) are two systemic granulomatous vasculitides affecting medium- and large-sized arteries. Similarities in GCA and TAK regarding the clinical presentation, the systemic inflammatory response and the distribution of the arterial lesions, have triggered a debate over the last decade about whether GCA and TAK represent two different diseases, or are age-associated different clinical phenotypes of the same disease. On the other hand, there are differences regarding epidemiology, several clinical features (eg, polymyalgia rheumatica in GCA) and treatment. The aim of this review is to present the latest data regarding this question and to shed some light on the differences and similarities between GCA and TAK regarding epidemiology, genetics, pathogenesis, histopathology, clinical presentation, imaging and treatment. The existing data in literature support the opinion that GCA and TAK are different clinical entities.}}, author = {{Stamatis, Pavlos}}, issn = {{2529-198X}}, language = {{eng}}, number = {{2}}, pages = {{174--182}}, publisher = {{Greek Rheumatology Society and Professional Association of Rheumatologists}}, series = {{Mediterranean Journal of Rheumatology}}, title = {{Giant Cell Arteritis versus Takayasu Arteritis: An Update}}, url = {{http://dx.doi.org/10.31138/mjr.31.2.174}}, doi = {{10.31138/mjr.31.2.174}}, volume = {{31}}, year = {{2020}}, }