Citral a fragrance allergen and irritant
(2003) In Contact Dermatitis 49(1). p.32-36- Abstract
- Citral is a well known contact allergen and a contact irritant. Routine patch testing in the past may have been restricted because of possible irritant (IR) patch test responses. 586 consecutive patients, with hand eczema, were patch tested with a selection of fragrances including citral 2% petrolatum and the European standard series. 28 of the patients showed a positive patch test reaction (+ to +++) to citral and 82 at least 1 IR patch test reaction and no positive patch test reaction to citral. A statistically significant association between a positive patch test reaction to citral and positive patch test reactions to other fragrances compared with IR reactions (n = 82) was established. The difference regarding fragrance history found... (More)
- Citral is a well known contact allergen and a contact irritant. Routine patch testing in the past may have been restricted because of possible irritant (IR) patch test responses. 586 consecutive patients, with hand eczema, were patch tested with a selection of fragrances including citral 2% petrolatum and the European standard series. 28 of the patients showed a positive patch test reaction (+ to +++) to citral and 82 at least 1 IR patch test reaction and no positive patch test reaction to citral. A statistically significant association between a positive patch test reaction to citral and positive patch test reactions to other fragrances compared with IR reactions (n = 82) was established. The difference regarding fragrance history found between those with IR and positive reactions to citral was not significant. Citral could be an allergen and/or irritant, worthy of further more extensive studies. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/293928
- author
- Heydorn, S ; Menne, T ; Andersen, KE ; Bruze, Magnus LU ; Svedman, Cecilia LU ; White, IR and Basketter, DA
- organization
- publishing date
- 2003
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- patch testing, fragrance, contact irritant, citral, contact allergen
- in
- Contact Dermatitis
- volume
- 49
- issue
- 1
- pages
- 32 - 36
- publisher
- Wiley-Blackwell
- external identifiers
-
- wos:000186891900006
- pmid:14641118
- scopus:0346753594
- ISSN
- 0105-1873
- DOI
- 10.1111/j.0105-1873.2003.00144.x
- language
- English
- LU publication?
- yes
- id
- 4d906fee-9b57-437f-a385-0baad701bf69 (old id 293928)
- date added to LUP
- 2016-04-01 12:16:15
- date last changed
- 2022-05-26 04:39:45
@article{4d906fee-9b57-437f-a385-0baad701bf69, abstract = {{Citral is a well known contact allergen and a contact irritant. Routine patch testing in the past may have been restricted because of possible irritant (IR) patch test responses. 586 consecutive patients, with hand eczema, were patch tested with a selection of fragrances including citral 2% petrolatum and the European standard series. 28 of the patients showed a positive patch test reaction (+ to +++) to citral and 82 at least 1 IR patch test reaction and no positive patch test reaction to citral. A statistically significant association between a positive patch test reaction to citral and positive patch test reactions to other fragrances compared with IR reactions (n = 82) was established. The difference regarding fragrance history found between those with IR and positive reactions to citral was not significant. Citral could be an allergen and/or irritant, worthy of further more extensive studies.}}, author = {{Heydorn, S and Menne, T and Andersen, KE and Bruze, Magnus and Svedman, Cecilia and White, IR and Basketter, DA}}, issn = {{0105-1873}}, keywords = {{patch testing; fragrance; contact irritant; citral; contact allergen}}, language = {{eng}}, number = {{1}}, pages = {{32--36}}, publisher = {{Wiley-Blackwell}}, series = {{Contact Dermatitis}}, title = {{Citral a fragrance allergen and irritant}}, url = {{http://dx.doi.org/10.1111/j.0105-1873.2003.00144.x}}, doi = {{10.1111/j.0105-1873.2003.00144.x}}, volume = {{49}}, year = {{2003}}, }