Factors associated with COVID-19 vaccine uptake among south African health care workers
(2024) In Vaccine 42(21).- Abstract
Background: Identifying factors associated with vaccine uptake among health care workers (HCWs) remains crucial to generating evidence aimed at guiding national COVID-19 vaccination and future infectious disease outbreak strategies. This study aimed to elucidate these factors, focusing on the interplay between socio-demographic, health, knowledge, beliefs and attitudinal indicators. Methods: This was a cross-sectional online survey administered to HCWs across South Africa between August and October 2022. Bivariate and Multivariate logistic regressions identified associations between COVID-19 vaccine uptake and demographics, occupational characteristics, general knowledge of and attitudes towards vaccination, perceived COVID-19 risk and... (More)
Background: Identifying factors associated with vaccine uptake among health care workers (HCWs) remains crucial to generating evidence aimed at guiding national COVID-19 vaccination and future infectious disease outbreak strategies. This study aimed to elucidate these factors, focusing on the interplay between socio-demographic, health, knowledge, beliefs and attitudinal indicators. Methods: This was a cross-sectional online survey administered to HCWs across South Africa between August and October 2022. Bivariate and Multivariate logistic regressions identified associations between COVID-19 vaccine uptake and demographics, occupational characteristics, general knowledge of and attitudes towards vaccination, perceived COVID-19 risk and perceived importance of COVID-19 vaccine attributes. Results: Analysis revealed high vaccine uptake rates among the sample of 5564 HCWs, with 87.6% of the sample vaccinated at the time of the study. Demographic measures significantly associated with vaccine uptake were age (P-value = 0.001), race (P-value = 0.021), religion (P-value = 0.004), and having a chronic illness (P-value <0.001). Belief and attitude measures significantly associated with vaccine uptake included: need for vaccines (P-value <0.001), perceived risk of infection (P-value = 0.001), perceived patient risk (P-value <0.001), and perceived vaccine knowledge (P-value <0.001). Multivariate analysis revealed that HCWs who listed their religion as African Spirituality (OR = 0.4; 95% CI = 0.2–0.7; P-value = 0.002) and had any occupation other than nurse or doctor (OR = 0.6; 95% CI = 0.4–0.8; P-value <0.001), were less likely to vaccinate, while HCWs who had a chronic condition (OR = 1.5; 95% CI = 1.2–2.0; P-value <0.001) were more likely to have been vaccinated. Conclusion: This study provides useful insights into the factors associated with and possibly driving COVID-19 vaccine uptake among HCWs in South Africa. These results add to a limited body of knowledge on contextual dynamics associated with vaccination programmes in Africa.
(Less)
- author
- George, Gavin LU ; Strauss, Michael ; Lansdell, Emma ; Nota, Phiwe ; Peters, Remco P.H. ; Brysiewicz, Petra ; Nadesan-Reddy, Nisha and Wassenaar, Douglas
- organization
- publishing date
- 2024-08
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- COVID-19, Health care workers, South Africa, Vaccines
- in
- Vaccine
- volume
- 42
- issue
- 21
- article number
- 126181
- publisher
- Elsevier
- external identifiers
-
- pmid:39111155
- scopus:85200463046
- ISSN
- 0264-410X
- DOI
- 10.1016/j.vaccine.2024.126181
- language
- English
- LU publication?
- yes
- id
- 2c0aa3a4-ca76-40c5-beaa-e0a698977b81
- date added to LUP
- 2024-09-10 15:11:13
- date last changed
- 2024-09-10 15:12:07
@article{2c0aa3a4-ca76-40c5-beaa-e0a698977b81,
abstract = {{<p>Background: Identifying factors associated with vaccine uptake among health care workers (HCWs) remains crucial to generating evidence aimed at guiding national COVID-19 vaccination and future infectious disease outbreak strategies. This study aimed to elucidate these factors, focusing on the interplay between socio-demographic, health, knowledge, beliefs and attitudinal indicators. Methods: This was a cross-sectional online survey administered to HCWs across South Africa between August and October 2022. Bivariate and Multivariate logistic regressions identified associations between COVID-19 vaccine uptake and demographics, occupational characteristics, general knowledge of and attitudes towards vaccination, perceived COVID-19 risk and perceived importance of COVID-19 vaccine attributes. Results: Analysis revealed high vaccine uptake rates among the sample of 5564 HCWs, with 87.6% of the sample vaccinated at the time of the study. Demographic measures significantly associated with vaccine uptake were age (P-value = 0.001), race (P-value = 0.021), religion (P-value = 0.004), and having a chronic illness (P-value <0.001). Belief and attitude measures significantly associated with vaccine uptake included: need for vaccines (P-value <0.001), perceived risk of infection (P-value = 0.001), perceived patient risk (P-value <0.001), and perceived vaccine knowledge (P-value <0.001). Multivariate analysis revealed that HCWs who listed their religion as African Spirituality (OR = 0.4; 95% CI = 0.2–0.7; P-value = 0.002) and had any occupation other than nurse or doctor (OR = 0.6; 95% CI = 0.4–0.8; P-value <0.001), were less likely to vaccinate, while HCWs who had a chronic condition (OR = 1.5; 95% CI = 1.2–2.0; P-value <0.001) were more likely to have been vaccinated. Conclusion: This study provides useful insights into the factors associated with and possibly driving COVID-19 vaccine uptake among HCWs in South Africa. These results add to a limited body of knowledge on contextual dynamics associated with vaccination programmes in Africa.</p>}},
author = {{George, Gavin and Strauss, Michael and Lansdell, Emma and Nota, Phiwe and Peters, Remco P.H. and Brysiewicz, Petra and Nadesan-Reddy, Nisha and Wassenaar, Douglas}},
issn = {{0264-410X}},
keywords = {{COVID-19; Health care workers; South Africa; Vaccines}},
language = {{eng}},
number = {{21}},
publisher = {{Elsevier}},
series = {{Vaccine}},
title = {{Factors associated with COVID-19 vaccine uptake among south African health care workers}},
url = {{http://dx.doi.org/10.1016/j.vaccine.2024.126181}},
doi = {{10.1016/j.vaccine.2024.126181}},
volume = {{42}},
year = {{2024}},
}