Genome-Wide Gene Birth–Death Dynamics Are Associated with Diet Breadth Variation in Lepidoptera
(2024) In Genome Biology and Evolution 16(7).- Abstract
Comparative analyses of gene birth–death dynamics have the potential to reveal gene families that played an important role in the evolution of morphological, behavioral, or physiological variation. Here, we used whole genomes of 30 species of butterflies and moths to identify gene birth–death dynamics among the Lepidoptera that are associated with specialist or generalist feeding strategies. Our work advances this field using a uniform set of annotated proteins for all genomes, investigating associations while correcting for phylogeny, and assessing all gene families rather than a priori subsets. We discovered that the sizes of several important gene families (e.g. those associated with pesticide resistance, xenobiotic detoxification,... (More)
Comparative analyses of gene birth–death dynamics have the potential to reveal gene families that played an important role in the evolution of morphological, behavioral, or physiological variation. Here, we used whole genomes of 30 species of butterflies and moths to identify gene birth–death dynamics among the Lepidoptera that are associated with specialist or generalist feeding strategies. Our work advances this field using a uniform set of annotated proteins for all genomes, investigating associations while correcting for phylogeny, and assessing all gene families rather than a priori subsets. We discovered that the sizes of several important gene families (e.g. those associated with pesticide resistance, xenobiotic detoxification, and/or protein digestion) are significantly correlated with diet breadth. We also found 22 gene families showing significant shifts in gene birth–death dynamics at the butterfly (Papilionoidea) crown node, the most notable of which was a family of pheromone receptors that underwent a contraction potentially linked with a shift to visual-based mate recognition. Our findings highlight the importance of uniform annotations, phylogenetic corrections, and unbiased gene family analyses in generating a list of candidate genes that warrant further exploration.
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- author
- Dort, Hanna ; van der Bijl, Wouter ; Wahlberg, Niklas LU ; Nylin, Sören and Wheat, Christopher W.
- organization
- publishing date
- 2024-07
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- butterflies, coevolution, comparative genomics, diet breadth, gene birth–death dynamics, insect–host plant interactions, Lepidoptera, specialization
- in
- Genome Biology and Evolution
- volume
- 16
- issue
- 7
- article number
- evae095
- publisher
- Oxford University Press
- external identifiers
-
- scopus:85198262605
- pmid:38976568
- ISSN
- 1759-6653
- DOI
- 10.1093/gbe/evae095
- language
- English
- LU publication?
- yes
- id
- 2fdc22f0-0b2f-41cc-8d9b-753ac01f51e4
- date added to LUP
- 2024-09-30 10:03:29
- date last changed
- 2024-10-04 18:20:43
@article{2fdc22f0-0b2f-41cc-8d9b-753ac01f51e4,
abstract = {{<p>Comparative analyses of gene birth–death dynamics have the potential to reveal gene families that played an important role in the evolution of morphological, behavioral, or physiological variation. Here, we used whole genomes of 30 species of butterflies and moths to identify gene birth–death dynamics among the Lepidoptera that are associated with specialist or generalist feeding strategies. Our work advances this field using a uniform set of annotated proteins for all genomes, investigating associations while correcting for phylogeny, and assessing all gene families rather than a priori subsets. We discovered that the sizes of several important gene families (e.g. those associated with pesticide resistance, xenobiotic detoxification, and/or protein digestion) are significantly correlated with diet breadth. We also found 22 gene families showing significant shifts in gene birth–death dynamics at the butterfly (Papilionoidea) crown node, the most notable of which was a family of pheromone receptors that underwent a contraction potentially linked with a shift to visual-based mate recognition. Our findings highlight the importance of uniform annotations, phylogenetic corrections, and unbiased gene family analyses in generating a list of candidate genes that warrant further exploration.</p>}},
author = {{Dort, Hanna and van der Bijl, Wouter and Wahlberg, Niklas and Nylin, Sören and Wheat, Christopher W.}},
issn = {{1759-6653}},
keywords = {{butterflies; coevolution; comparative genomics; diet breadth; gene birth–death dynamics; insect–host plant interactions; Lepidoptera; specialization}},
language = {{eng}},
number = {{7}},
publisher = {{Oxford University Press}},
series = {{Genome Biology and Evolution}},
title = {{Genome-Wide Gene Birth–Death Dynamics Are Associated with Diet Breadth Variation in Lepidoptera}},
url = {{http://dx.doi.org/10.1093/gbe/evae095}},
doi = {{10.1093/gbe/evae095}},
volume = {{16}},
year = {{2024}},
}