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Psychosomatic factors in pruritus

Ley, Hong Liang ; Tey, HL and Wallengren, Joanna LU orcid (2013) In Clinics in Dermatology 31(1). p.31-40
Abstract
Pruritus and psyche are intricately and reciprocally related, with psychophysiological evidence and psychopathological explanations helping us to understand their complex association. Their interaction may be conceptualized and classified into 3 groups: pruritic diseases with psychiatric sequelae, pruritic diseases aggravated by psychosocial factors, and psychiatric disorders causing pruritus. Management of chronic pruritus is directed at treating the underlying causes and adopting a multidisciplinary approach to address the dermatologic, somatosensory, cognitive, and emotional aspects. Pharmcotherapeutic agents that are useful for chronic pruritus with comorbid depression and/or anxiety comprise selective serotonin reuptake inhibitors,... (More)
Pruritus and psyche are intricately and reciprocally related, with psychophysiological evidence and psychopathological explanations helping us to understand their complex association. Their interaction may be conceptualized and classified into 3 groups: pruritic diseases with psychiatric sequelae, pruritic diseases aggravated by psychosocial factors, and psychiatric disorders causing pruritus. Management of chronic pruritus is directed at treating the underlying causes and adopting a multidisciplinary approach to address the dermatologic, somatosensory, cognitive, and emotional aspects. Pharmcotherapeutic agents that are useful for chronic pruritus with comorbid depression and/or anxiety comprise selective serotonin reuptake inhibitors, mirtazapine, tricyclic antidepressants (amitriptyline and doxepin), and anticonvulsants (gabapentin, pregabalin); the role of neurokinin receptor-1 antagonists awaits verification. Antipsychotics are required for treating itch and formication associated with schizophrenia and delusion of parasitosis (including Morgellons disease). (c) 2013 Elsevier Inc. All rights reserved. (Less)
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author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Clinics in Dermatology
volume
31
issue
1
pages
31 - 40
publisher
Elsevier
external identifiers
  • wos:000313316500005
  • scopus:84871070281
  • pmid:23245971
ISSN
0738-081X
DOI
10.1016/j.clindermatol.2011.11.004
language
English
LU publication?
yes
id
0b4b6bf5-61a9-467a-84a1-e8ec85473652 (old id 3470645)
date added to LUP
2016-04-01 14:55:32
date last changed
2022-08-07 08:05:46
@article{0b4b6bf5-61a9-467a-84a1-e8ec85473652,
  abstract     = {{Pruritus and psyche are intricately and reciprocally related, with psychophysiological evidence and psychopathological explanations helping us to understand their complex association. Their interaction may be conceptualized and classified into 3 groups: pruritic diseases with psychiatric sequelae, pruritic diseases aggravated by psychosocial factors, and psychiatric disorders causing pruritus. Management of chronic pruritus is directed at treating the underlying causes and adopting a multidisciplinary approach to address the dermatologic, somatosensory, cognitive, and emotional aspects. Pharmcotherapeutic agents that are useful for chronic pruritus with comorbid depression and/or anxiety comprise selective serotonin reuptake inhibitors, mirtazapine, tricyclic antidepressants (amitriptyline and doxepin), and anticonvulsants (gabapentin, pregabalin); the role of neurokinin receptor-1 antagonists awaits verification. Antipsychotics are required for treating itch and formication associated with schizophrenia and delusion of parasitosis (including Morgellons disease). (c) 2013 Elsevier Inc. All rights reserved.}},
  author       = {{Ley, Hong Liang and Tey, HL and Wallengren, Joanna}},
  issn         = {{0738-081X}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{31--40}},
  publisher    = {{Elsevier}},
  series       = {{Clinics in Dermatology}},
  title        = {{Psychosomatic factors in pruritus}},
  url          = {{http://dx.doi.org/10.1016/j.clindermatol.2011.11.004}},
  doi          = {{10.1016/j.clindermatol.2011.11.004}},
  volume       = {{31}},
  year         = {{2013}},
}