Immunome: a reference set of genes and proteins for systems biology of the human immune system.
(2006) In Cellular Immunology 244(2). p.87-89- Abstract
- The function of the immune system requires coordinated expression and action of many genes and proteins. With the emergence of high throughput technologies it has become possible to target human immunity from a systems biology point of view. To perform systems biology studies with comparable results we need not just a reference gene and protein set but also useful and descriptive reference categories for the immunity related genes. We have identified and collected the genes and proteins of the essential human immunome. The 847 genes and proteins were annotated, and characterized, and they were categorized according to their functions, protein domains and Gene Ontology terms. The reference set and the categories are freely available in the... (More)
- The function of the immune system requires coordinated expression and action of many genes and proteins. With the emergence of high throughput technologies it has become possible to target human immunity from a systems biology point of view. To perform systems biology studies with comparable results we need not just a reference gene and protein set but also useful and descriptive reference categories for the immunity related genes. We have identified and collected the genes and proteins of the essential human immunome. The 847 genes and proteins were annotated, and characterized, and they were categorized according to their functions, protein domains and Gene Ontology terms. The reference set and the categories are freely available in the immunome database at http://bioinf.uta.fi/Immunome/. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3635280
- author
- Ortutay, Csaba and Vihinen, Mauno LU
- publishing date
- 2006
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Immune System: physiology, Immunity: genetics
- in
- Cellular Immunology
- volume
- 244
- issue
- 2
- pages
- 87 - 89
- publisher
- Elsevier
- external identifiers
-
- pmid:17434156
- scopus:34248370076
- pmid:17434156
- ISSN
- 0008-8749
- DOI
- 10.1016/j.cellimm.2007.01.012
- language
- English
- LU publication?
- no
- id
- c8286183-2683-4665-a3e3-c23c365b6524 (old id 3635280)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/17434156?dopt=Abstract
- date added to LUP
- 2016-04-04 09:27:57
- date last changed
- 2022-01-29 18:00:12
@article{c8286183-2683-4665-a3e3-c23c365b6524, abstract = {{The function of the immune system requires coordinated expression and action of many genes and proteins. With the emergence of high throughput technologies it has become possible to target human immunity from a systems biology point of view. To perform systems biology studies with comparable results we need not just a reference gene and protein set but also useful and descriptive reference categories for the immunity related genes. We have identified and collected the genes and proteins of the essential human immunome. The 847 genes and proteins were annotated, and characterized, and they were categorized according to their functions, protein domains and Gene Ontology terms. The reference set and the categories are freely available in the immunome database at http://bioinf.uta.fi/Immunome/.}}, author = {{Ortutay, Csaba and Vihinen, Mauno}}, issn = {{0008-8749}}, keywords = {{Immune System: physiology; Immunity: genetics}}, language = {{eng}}, number = {{2}}, pages = {{87--89}}, publisher = {{Elsevier}}, series = {{Cellular Immunology}}, title = {{Immunome: a reference set of genes and proteins for systems biology of the human immune system.}}, url = {{http://dx.doi.org/10.1016/j.cellimm.2007.01.012}}, doi = {{10.1016/j.cellimm.2007.01.012}}, volume = {{244}}, year = {{2006}}, }