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Overexpression of translocation-associated fusion genes of FGFRI, MYC, NPMI, and DEK, but absence of the translocations in acute myeloid leukemia. A microarray analysis.

Larramendy, Marcelo L ; Niini, Tarja ; Elonen, Erkki ; Nagy, Bálint ; Ollila, Juha ; Vihinen, Mauno LU orcid and Knuutila, Sakari (2002) In Haematologica 87(6). p.569-577
Abstract
Translocation-associated gene fusions are well recognized in acute myeloid leukemia. Other molecular genetic changes are less well known. The novel cDNA technology has opened the avenue to large-scale gene expression analysis. Our aim was to perform cDNA microarray analysis of acute myeloid leukemia (AML).
Please use this url to cite or link to this publication:
author
; ; ; ; ; and
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Receptor Protein-Tyrosine Kinases: genetics, RNA: metabolism, Oncogenes: physiology, Oncogene Proteins: genetics, Nuclear Proteins: physiology, Nuclear Proteins: genetics, Neoplasm Proteins: physiology, Neoplasm Proteins: genetics, Myeloid: genetics, Leukemia, myc: physiology, myc: genetics, bcl-2: physiology, bcl-2: genetics, Genes, Gene Expression Regulation: physiology, DNA-Binding Proteins: physiology, DNA-Binding Proteins: genetics, Carrier Proteins: physiology, Carrier Proteins: genetics, Calcium-Calmodulin-Dependent Protein Kinases: genetics, Calcium-Calmodulin-Dependent Protein Kinases: physiology, Receptor Protein-Tyrosine Kinases: physiology, Receptor, Macrophage Colony-Stimulating Factor: genetics, Macrophage Colony-Stimulating Factor: physiology, Receptors, Fibroblast Growth Factor: genetics, Fibroblast Growth Factor: physiology, Viral Proteins: genetics, Viral Proteins: physiology
in
Haematologica
volume
87
issue
6
pages
569 - 577
publisher
Ferrata Storti Foundation
external identifiers
  • pmid:12031912
ISSN
1592-8721
language
English
LU publication?
no
id
0d6e4053-84c0-405e-aaa9-85886b362af2 (old id 3635600)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/12031912?dopt=Abstract
date added to LUP
2016-04-04 09:21:35
date last changed
2020-05-29 16:55:56
@article{0d6e4053-84c0-405e-aaa9-85886b362af2,
  abstract     = {{Translocation-associated gene fusions are well recognized in acute myeloid leukemia. Other molecular genetic changes are less well known. The novel cDNA technology has opened the avenue to large-scale gene expression analysis. Our aim was to perform cDNA microarray analysis of acute myeloid leukemia (AML).}},
  author       = {{Larramendy, Marcelo L and Niini, Tarja and Elonen, Erkki and Nagy, Bálint and Ollila, Juha and Vihinen, Mauno and Knuutila, Sakari}},
  issn         = {{1592-8721}},
  keywords     = {{Receptor Protein-Tyrosine Kinases: genetics; RNA: metabolism; Oncogenes: physiology; Oncogene Proteins: genetics; Nuclear Proteins: physiology; Nuclear Proteins: genetics; Neoplasm Proteins: physiology; Neoplasm Proteins: genetics; Myeloid: genetics; Leukemia; myc: physiology; myc: genetics; bcl-2: physiology; bcl-2: genetics; Genes; Gene Expression Regulation: physiology; DNA-Binding Proteins: physiology; DNA-Binding Proteins: genetics; Carrier Proteins: physiology; Carrier Proteins: genetics; Calcium-Calmodulin-Dependent Protein Kinases: genetics; Calcium-Calmodulin-Dependent Protein Kinases: physiology; Receptor Protein-Tyrosine Kinases: physiology; Receptor; Macrophage Colony-Stimulating Factor: genetics; Macrophage Colony-Stimulating Factor: physiology; Receptors; Fibroblast Growth Factor: genetics; Fibroblast Growth Factor: physiology; Viral Proteins: genetics; Viral Proteins: physiology}},
  language     = {{eng}},
  number       = {{6}},
  pages        = {{569--577}},
  publisher    = {{Ferrata Storti Foundation}},
  series       = {{Haematologica}},
  title        = {{Overexpression of translocation-associated fusion genes of FGFRI, MYC, NPMI, and DEK, but absence of the translocations in acute myeloid leukemia. A microarray analysis.}},
  url          = {{http://www.ncbi.nlm.nih.gov/pubmed/12031912?dopt=Abstract}},
  volume       = {{87}},
  year         = {{2002}},
}