Calvarial bone healing under spring distension at continuous forces
(2006) In Annals of Plastic Surgery 57(5). p.561-568- Abstract
- The aim of the present study was to evaluate in young animals the dynamics of calvarial bone healing when exposing a bone defect to continuous forces for up to 13 weeks. Six-week-old rabbits after a sagittal suture strip craniectomy were randomized for either of the following protocols: (1) no spring was applied (n = 7); (2) a titanium-molybdenum alloy (TMA) lower-force spring was inserted across the craniectomy gap (n = 9); (3) a stainless steel (SS) higher-force spring was applied (n = 8), or (4) sham operation (n = 8). Results showed that the surgically created calvarial bone gap was after 3 weeks kept widened both when a spring of lower force (TMA) and when a spring exerting a higher force (SS) was applied. At 6 weeks, none of the... (More)
- The aim of the present study was to evaluate in young animals the dynamics of calvarial bone healing when exposing a bone defect to continuous forces for up to 13 weeks. Six-week-old rabbits after a sagittal suture strip craniectomy were randomized for either of the following protocols: (1) no spring was applied (n = 7); (2) a titanium-molybdenum alloy (TMA) lower-force spring was inserted across the craniectomy gap (n = 9); (3) a stainless steel (SS) higher-force spring was applied (n = 8), or (4) sham operation (n = 8). Results showed that the surgically created calvarial bone gap was after 3 weeks kept widened both when a spring of lower force (TMA) and when a spring exerting a higher force (SS) was applied. At 6 weeks, none of the rabbits of the spring-exposed (2 and 3) groups had any bone bridging the gap, while bone bridging was visible in animals of the 2 groups (I and 4) lacking springs. Strikingly enough, in both spring-treated groups, the surgically created defect was still after 13 weeks incompletely bridged by bone, interposed by connective tissue, most evidently in those exposed to higher forces (SS). In contrast, a normal sagittal suture enclosed by lamellar bone was seen in both the sham and the strip groups. We conclude that exposing a surgically created calvarial bone defect to continuous mechanical forces delayed the bridging of the bone defect by at least 13 weeks, even if the force exerted by either spring was very low. In any case, when a higher force (SS group) was applied, the bone reunion was efficiently prevented. No side effects were recognized. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/384240
- author
- Pignatti, Marco ; Hansson, Hans-Arne and Gewalli, Fredrik LU
- organization
- publishing date
- 2006
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- sagittal suture, calvaria, springs, expansion, bone healing, distraction
- in
- Annals of Plastic Surgery
- volume
- 57
- issue
- 5
- pages
- 561 - 568
- publisher
- Lippincott Williams & Wilkins
- external identifiers
-
- wos:000241533300015
- scopus:33750333227
- ISSN
- 1536-3708
- DOI
- 10.1097/01.sap.0000229019.29857.14
- language
- English
- LU publication?
- yes
- id
- d487ff02-01bd-4e20-93fd-32e3a169314c (old id 384240)
- date added to LUP
- 2016-04-01 12:02:49
- date last changed
- 2022-01-26 22:01:50
@article{d487ff02-01bd-4e20-93fd-32e3a169314c,
abstract = {{The aim of the present study was to evaluate in young animals the dynamics of calvarial bone healing when exposing a bone defect to continuous forces for up to 13 weeks. Six-week-old rabbits after a sagittal suture strip craniectomy were randomized for either of the following protocols: (1) no spring was applied (n = 7); (2) a titanium-molybdenum alloy (TMA) lower-force spring was inserted across the craniectomy gap (n = 9); (3) a stainless steel (SS) higher-force spring was applied (n = 8), or (4) sham operation (n = 8). Results showed that the surgically created calvarial bone gap was after 3 weeks kept widened both when a spring of lower force (TMA) and when a spring exerting a higher force (SS) was applied. At 6 weeks, none of the rabbits of the spring-exposed (2 and 3) groups had any bone bridging the gap, while bone bridging was visible in animals of the 2 groups (I and 4) lacking springs. Strikingly enough, in both spring-treated groups, the surgically created defect was still after 13 weeks incompletely bridged by bone, interposed by connective tissue, most evidently in those exposed to higher forces (SS). In contrast, a normal sagittal suture enclosed by lamellar bone was seen in both the sham and the strip groups. We conclude that exposing a surgically created calvarial bone defect to continuous mechanical forces delayed the bridging of the bone defect by at least 13 weeks, even if the force exerted by either spring was very low. In any case, when a higher force (SS group) was applied, the bone reunion was efficiently prevented. No side effects were recognized.}},
author = {{Pignatti, Marco and Hansson, Hans-Arne and Gewalli, Fredrik}},
issn = {{1536-3708}},
keywords = {{sagittal suture; calvaria; springs; expansion; bone healing; distraction}},
language = {{eng}},
number = {{5}},
pages = {{561--568}},
publisher = {{Lippincott Williams & Wilkins}},
series = {{Annals of Plastic Surgery}},
title = {{Calvarial bone healing under spring distension at continuous forces}},
url = {{http://dx.doi.org/10.1097/01.sap.0000229019.29857.14}},
doi = {{10.1097/01.sap.0000229019.29857.14}},
volume = {{57}},
year = {{2006}},
}