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A Narrative Review of the Association of Obstructive Sleep Apnea with Hypertension : How to Treat Both When They Coexist?

Altay, Servet ; Fırat, Selma and Peker, Yüksel LU (2023) In Journal of Clinical Medicine 12(12).
Abstract

Hypertension (HT) is a worldwide public health issue and an essential risk factor for cardiovascular and cerebrovascular diseases. Obstructive sleep apnea (OSA) is a condition characterized by recurrent episodes of apnea and hypopnea as a consequence of partial or complete obstruction of the upper airways due to anatomic and/or functional disturbances. There is mounting evidence of a relationship between OSA and HT. In patients with OSA, HT is predominantly nocturnal and characterized by high diastolic blood pressure and usually by a nondipping pattern. Optimizing the blood pressure control is recommended in the current guidelines as the first treatment option in hypertensive patients with OSA. Continuous positive airway pressure (CPAP)... (More)

Hypertension (HT) is a worldwide public health issue and an essential risk factor for cardiovascular and cerebrovascular diseases. Obstructive sleep apnea (OSA) is a condition characterized by recurrent episodes of apnea and hypopnea as a consequence of partial or complete obstruction of the upper airways due to anatomic and/or functional disturbances. There is mounting evidence of a relationship between OSA and HT. In patients with OSA, HT is predominantly nocturnal and characterized by high diastolic blood pressure and usually by a nondipping pattern. Optimizing the blood pressure control is recommended in the current guidelines as the first treatment option in hypertensive patients with OSA. Continuous positive airway pressure (CPAP) therapy may reduce blood pressure, albeit only slightly as a stand-alone treatment. CPAP, as an add-on treatment to antihypertensive medication, appears to be an efficient treatment modality when both conditions coexist. This narrative review aims to summarize the current perspectives on the association of OSA with HT and the treatment options available for adults with OSA-related HT.

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publishing date
type
Contribution to journal
publication status
published
subject
keywords
hypertension, narrative review, obstructive sleep apnea
in
Journal of Clinical Medicine
volume
12
issue
12
article number
4144
publisher
MDPI AG
external identifiers
  • pmid:37373837
  • scopus:85163722153
ISSN
2077-0383
DOI
10.3390/jcm12124144
language
English
LU publication?
yes
id
3aef0b41-b9ba-4089-b349-1b63d20b4107
date added to LUP
2023-09-15 13:36:31
date last changed
2024-12-14 02:15:15
@article{3aef0b41-b9ba-4089-b349-1b63d20b4107,
  abstract     = {{<p>Hypertension (HT) is a worldwide public health issue and an essential risk factor for cardiovascular and cerebrovascular diseases. Obstructive sleep apnea (OSA) is a condition characterized by recurrent episodes of apnea and hypopnea as a consequence of partial or complete obstruction of the upper airways due to anatomic and/or functional disturbances. There is mounting evidence of a relationship between OSA and HT. In patients with OSA, HT is predominantly nocturnal and characterized by high diastolic blood pressure and usually by a nondipping pattern. Optimizing the blood pressure control is recommended in the current guidelines as the first treatment option in hypertensive patients with OSA. Continuous positive airway pressure (CPAP) therapy may reduce blood pressure, albeit only slightly as a stand-alone treatment. CPAP, as an add-on treatment to antihypertensive medication, appears to be an efficient treatment modality when both conditions coexist. This narrative review aims to summarize the current perspectives on the association of OSA with HT and the treatment options available for adults with OSA-related HT.</p>}},
  author       = {{Altay, Servet and Fırat, Selma and Peker, Yüksel}},
  issn         = {{2077-0383}},
  keywords     = {{hypertension; narrative review; obstructive sleep apnea}},
  language     = {{eng}},
  number       = {{12}},
  publisher    = {{MDPI AG}},
  series       = {{Journal of Clinical Medicine}},
  title        = {{A Narrative Review of the Association of Obstructive Sleep Apnea with Hypertension : How to Treat Both When They Coexist?}},
  url          = {{http://dx.doi.org/10.3390/jcm12124144}},
  doi          = {{10.3390/jcm12124144}},
  volume       = {{12}},
  year         = {{2023}},
}