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Retrospective Artifact Elimination in MEGA-PRESS using a Correlation Approach

Tapper, Sofie ; Tisell, Anders ; Helms, Gunther LU orcid and Lundberg, Peter (2019) In Magnetic Resonance in Medicine 81(4). p.2223-2237
Abstract
Purpose
To develop a method for retrospective artifact elimination of MRS data. This retrospective method was based on an approach that combines jackknife analyses with the correlation of spectral windows, and therefore termed “JKC.”

Methods
Twelve healthy volunteers performed 3 separate measurement protocols using a 3T MR system. One protocol consisted of 2 cerebellar MEGA‐PRESS measurements: 1 reference and 1 measurement including head movements. One‐third of the artifact‐influenced datasets were treated as training data for the implementation the JKC method, and the rest were used for validation.

Results
The implemented JKC method correctly characterized most of the validation data. Additionally, after... (More)
Purpose
To develop a method for retrospective artifact elimination of MRS data. This retrospective method was based on an approach that combines jackknife analyses with the correlation of spectral windows, and therefore termed “JKC.”

Methods
Twelve healthy volunteers performed 3 separate measurement protocols using a 3T MR system. One protocol consisted of 2 cerebellar MEGA‐PRESS measurements: 1 reference and 1 measurement including head movements. One‐third of the artifact‐influenced datasets were treated as training data for the implementation the JKC method, and the rest were used for validation.

Results
The implemented JKC method correctly characterized most of the validation data. Additionally, after elimination of the detected artifacts, the resulting concentrations were much closer to those computed for the reference datasets. Moreover, when the JKC method was applied to the reference data, the estimated concentrations were not affected, compared with standard averaging.

Conclusion
The implemented JKC method can be applied without any extra cost to MRS data, regardless of whether the dataset has been contaminated by artifacts. Furthermore, the results indicate that the JKC method could be used as a quality control of a dataset, or as an indication of whether a shift in voxel placement has occurred during the measurement.
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author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Magnetic Resonance in Medicine
volume
81
issue
4
pages
15 pages
publisher
John Wiley & Sons Inc.
external identifiers
  • scopus:85056358584
  • pmid:30417930
ISSN
1522-2594
DOI
10.1002/mrm.27590
language
English
LU publication?
yes
id
3f8744f5-0c4d-4bd5-9142-db4c6ed699ed
date added to LUP
2018-11-12 19:25:25
date last changed
2022-04-25 18:36:17
@article{3f8744f5-0c4d-4bd5-9142-db4c6ed699ed,
  abstract     = {{Purpose<br/>To develop a method for retrospective artifact elimination of MRS data. This retrospective method was based on an approach that combines jackknife analyses with the correlation of spectral windows, and therefore termed “JKC.”<br/><br/>Methods<br/>Twelve healthy volunteers performed 3 separate measurement protocols using a 3T MR system. One protocol consisted of 2 cerebellar MEGA‐PRESS measurements: 1 reference and 1 measurement including head movements. One‐third of the artifact‐influenced datasets were treated as training data for the implementation the JKC method, and the rest were used for validation.<br/><br/>Results<br/>The implemented JKC method correctly characterized most of the validation data. Additionally, after elimination of the detected artifacts, the resulting concentrations were much closer to those computed for the reference datasets. Moreover, when the JKC method was applied to the reference data, the estimated concentrations were not affected, compared with standard averaging.<br/><br/>Conclusion<br/>The implemented JKC method can be applied without any extra cost to MRS data, regardless of whether the dataset has been contaminated by artifacts. Furthermore, the results indicate that the JKC method could be used as a quality control of a dataset, or as an indication of whether a shift in voxel placement has occurred during the measurement.<br/>}},
  author       = {{Tapper, Sofie and Tisell, Anders and Helms, Gunther and Lundberg, Peter}},
  issn         = {{1522-2594}},
  language     = {{eng}},
  number       = {{4}},
  pages        = {{2223--2237}},
  publisher    = {{John Wiley & Sons Inc.}},
  series       = {{Magnetic Resonance in Medicine}},
  title        = {{Retrospective Artifact Elimination in MEGA-PRESS using a Correlation Approach}},
  url          = {{http://dx.doi.org/10.1002/mrm.27590}},
  doi          = {{10.1002/mrm.27590}},
  volume       = {{81}},
  year         = {{2019}},
}