Cyclin e overexpression reduces infiltrative growth in breast cancer - Yet another link between proliferation control and tumor invasion
(2006) In Cell Cycle 5(6). p.606-609- Abstract
- Overexpression of cyclin E is strongly linked to an aggressive phenotype and poor prognosis in breast cancer. Unexpectedly, it has been shown that cyclin E overexpression decreases mobility and invasiveness of breast cancer cells. In fact, in a study of 985 breast cancers, cyclin E correlated with less infiltrative growth. This suggests a novel function for cyclin E in breast cancer tumorigenesis and a mutual control of proliferation and invasive behavior.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/406224
- author
- Berglund, Pontus LU and Landberg, Göran LU
- organization
- publishing date
- 2006
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- medullary breast, proliferation, invasion, breast cancer, cyclin E, microarray, cancer
- in
- Cell Cycle
- volume
- 5
- issue
- 6
- pages
- 606 - 609
- publisher
- Landes Bioscience
- external identifiers
-
- pmid:16582601
- wos:000238282400015
- scopus:33645310632
- ISSN
- 1551-4005
- language
- English
- LU publication?
- yes
- id
- 73480504-3aab-46cb-82a4-5f52a8256f70 (old id 406224)
- alternative location
- http://www.landesbioscience.com/journals/cc/abstract.php?id=2569
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16582601&dopt=Abstract
- date added to LUP
- 2016-04-01 11:34:42
- date last changed
- 2022-01-26 07:15:06
@article{73480504-3aab-46cb-82a4-5f52a8256f70, abstract = {{Overexpression of cyclin E is strongly linked to an aggressive phenotype and poor prognosis in breast cancer. Unexpectedly, it has been shown that cyclin E overexpression decreases mobility and invasiveness of breast cancer cells. In fact, in a study of 985 breast cancers, cyclin E correlated with less infiltrative growth. This suggests a novel function for cyclin E in breast cancer tumorigenesis and a mutual control of proliferation and invasive behavior.}}, author = {{Berglund, Pontus and Landberg, Göran}}, issn = {{1551-4005}}, keywords = {{medullary breast; proliferation; invasion; breast cancer; cyclin E; microarray; cancer}}, language = {{eng}}, number = {{6}}, pages = {{606--609}}, publisher = {{Landes Bioscience}}, series = {{Cell Cycle}}, title = {{Cyclin e overexpression reduces infiltrative growth in breast cancer - Yet another link between proliferation control and tumor invasion}}, url = {{http://www.landesbioscience.com/journals/cc/abstract.php?id=2569}}, volume = {{5}}, year = {{2006}}, }