The involvement of cellular proliferation status in the expression of the human proto-oncogene DEK
(2006) In Haematologica 91(2). p.268-269- Abstract
- The role of the DEK protein, involved in the leukemia-associated fusion protein DEK-CAN, is not yet known. In this study, we show a higher expression of DEK mRNA in immature cells than in mature cells. Furthermore, a correlation between DEK expression and cell proliferation was demonstrated, suggesting that DEK plays a role in the proliferation of hematopoietic cells and raising the question of whether the DEK-CAN fusion protein might perturb regulation of proliferation in leukemic cells.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/417502
- author
- Ageberg, Malin LU ; Gullberg, Urban LU and Lindmark, Anders LU
- organization
- publishing date
- 2006
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- leukemia, DEK, proliferation
- in
- Haematologica
- volume
- 91
- issue
- 2
- pages
- 268 - 269
- publisher
- Ferrata Storti Foundation
- external identifiers
-
- pmid:16461319
- wos:000235481300031
- scopus:33644525948
- ISSN
- 1592-8721
- language
- English
- LU publication?
- yes
- id
- 23d1cfe4-0177-4202-bb01-f468ecc3102f (old id 417502)
- alternative location
- http://www.haematologica.org/journal/2006/910268.pdf
- date added to LUP
- 2016-04-01 16:51:13
- date last changed
- 2022-04-23 00:55:04
@article{23d1cfe4-0177-4202-bb01-f468ecc3102f, abstract = {{The role of the DEK protein, involved in the leukemia-associated fusion protein DEK-CAN, is not yet known. In this study, we show a higher expression of DEK mRNA in immature cells than in mature cells. Furthermore, a correlation between DEK expression and cell proliferation was demonstrated, suggesting that DEK plays a role in the proliferation of hematopoietic cells and raising the question of whether the DEK-CAN fusion protein might perturb regulation of proliferation in leukemic cells.}}, author = {{Ageberg, Malin and Gullberg, Urban and Lindmark, Anders}}, issn = {{1592-8721}}, keywords = {{leukemia; DEK; proliferation}}, language = {{eng}}, number = {{2}}, pages = {{268--269}}, publisher = {{Ferrata Storti Foundation}}, series = {{Haematologica}}, title = {{The involvement of cellular proliferation status in the expression of the human proto-oncogene DEK}}, url = {{http://www.haematologica.org/journal/2006/910268.pdf}}, volume = {{91}}, year = {{2006}}, }