Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Contact dermatitis in children caused by diabetes devices

Alves da Silva, Catarina ; Bregnhøj, Anne ; Mowitz, Martin LU ; Bruze, Magnus LU ; Andersen, Klaus Ejner and Sommerlund, Mette (2022) In Contact Dermatitis 87(5). p.406-413
Abstract

Background: Insulin pumps and glucose monitoring devices improve diabetes mellitus control and enhance patients' quality of life. However, a growing number of adverse cutaneous reactions related to the use of these devices have been reported. Objective: To investigate the culprits of localized contact dermatitis in paediatric patients with diabetes caused by insulin pumps and glucose monitoring devices. Methods: Retrospective analysis of 15 paediatric patients patch tested as part of a clinical investigation for skin reactions associated with insulin pumps and glucose monitoring devices. Results: Seven patients had positive patch test reactions to isobornyl acrylate (IBOA) and five had positive reactions to benzoyl peroxide (BP).... (More)

Background: Insulin pumps and glucose monitoring devices improve diabetes mellitus control and enhance patients' quality of life. However, a growing number of adverse cutaneous reactions related to the use of these devices have been reported. Objective: To investigate the culprits of localized contact dermatitis in paediatric patients with diabetes caused by insulin pumps and glucose monitoring devices. Methods: Retrospective analysis of 15 paediatric patients patch tested as part of a clinical investigation for skin reactions associated with insulin pumps and glucose monitoring devices. Results: Seven patients had positive patch test reactions to isobornyl acrylate (IBOA) and five had positive reactions to benzoyl peroxide (BP). Positive patch test reactions to materials from the glucose sensor and/or insulin pump were seen in 10 of the 15 patients. Three had positive reactions to adhesive remover wipe from Smith and Nephew Remove and four had reactions to EMLA plaster. Conclusion: A high share of patients showed positive reactions to IBOA and/or their medical devices (insulin pumps or glucose devices). A third of patients showed positive reactions to BP. The presence of additional unidentified allergens cannot be excluded, highlighting the importance of access to a full description of the chemical composition of the devices.

(Less)
Please use this url to cite or link to this publication:
author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
allergic contact dermatitis, benzoyl peroxide, children, diabetes mellitus, gas chromatography–mass spectrometry, glucose sensors, insulin infusion sets, irritant contact dermatitis, isobornyl acrylate, sesquiterpene lactone mix
in
Contact Dermatitis
volume
87
issue
5
pages
406 - 413
publisher
Wiley-Blackwell
external identifiers
  • scopus:85131739831
  • pmid:35634681
ISSN
0105-1873
DOI
10.1111/cod.14166
language
English
LU publication?
yes
id
42d7de3f-b8f2-4b8f-9c59-1a8e9beee3f1
date added to LUP
2022-09-21 15:12:15
date last changed
2024-06-28 23:32:18
@article{42d7de3f-b8f2-4b8f-9c59-1a8e9beee3f1,
  abstract     = {{<p>Background: Insulin pumps and glucose monitoring devices improve diabetes mellitus control and enhance patients' quality of life. However, a growing number of adverse cutaneous reactions related to the use of these devices have been reported. Objective: To investigate the culprits of localized contact dermatitis in paediatric patients with diabetes caused by insulin pumps and glucose monitoring devices. Methods: Retrospective analysis of 15 paediatric patients patch tested as part of a clinical investigation for skin reactions associated with insulin pumps and glucose monitoring devices. Results: Seven patients had positive patch test reactions to isobornyl acrylate (IBOA) and five had positive reactions to benzoyl peroxide (BP). Positive patch test reactions to materials from the glucose sensor and/or insulin pump were seen in 10 of the 15 patients. Three had positive reactions to adhesive remover wipe from Smith and Nephew Remove and four had reactions to EMLA plaster. Conclusion: A high share of patients showed positive reactions to IBOA and/or their medical devices (insulin pumps or glucose devices). A third of patients showed positive reactions to BP. The presence of additional unidentified allergens cannot be excluded, highlighting the importance of access to a full description of the chemical composition of the devices.</p>}},
  author       = {{Alves da Silva, Catarina and Bregnhøj, Anne and Mowitz, Martin and Bruze, Magnus and Andersen, Klaus Ejner and Sommerlund, Mette}},
  issn         = {{0105-1873}},
  keywords     = {{allergic contact dermatitis; benzoyl peroxide; children; diabetes mellitus; gas chromatography–mass spectrometry; glucose sensors; insulin infusion sets; irritant contact dermatitis; isobornyl acrylate; sesquiterpene lactone mix}},
  language     = {{eng}},
  number       = {{5}},
  pages        = {{406--413}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Contact Dermatitis}},
  title        = {{Contact dermatitis in children caused by diabetes devices}},
  url          = {{http://dx.doi.org/10.1111/cod.14166}},
  doi          = {{10.1111/cod.14166}},
  volume       = {{87}},
  year         = {{2022}},
}