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Sociodemographic and clinical characteristics of 1,234 individuals diagnosed with trichotillomania in the Swedish National Patient Register

Farhat, Luis C. ; Isomura, Kayoko ; Fernández de la Cruz, Lorena ; Sidorchuk, Anna ; Kuja-Halkola, Ralf ; Brikell, Isabell ; Chang, Zheng ; D’Onofrio, Brian M. ; Larsson, Henrik and Lichtenstein, Paul , et al. (2025) In Scientific Reports 15(1).
Abstract

Trichotillomania is an understudied, underrecognized, and difficult-to-treat psychiatric disorder that affects about 1–2% of the population, predominantly women. This study aimed to characterize the sociodemographic and clinical characteristics of a Swedish cohort of individuals with a diagnosis of trichotillomania assigned in specialist services across the country. Through the Swedish National Patient Register, we identified all individuals with an ICD-10 diagnosis of trichotillomania between January 1st, 1997 and December 31st, 2020. The cohort included 1,234 individuals, with a median age at first diagnosis of 25 years (interquartile range, 16–35). Most individuals were female (85%) and single (82%). Most (79%)... (More)

Trichotillomania is an understudied, underrecognized, and difficult-to-treat psychiatric disorder that affects about 1–2% of the population, predominantly women. This study aimed to characterize the sociodemographic and clinical characteristics of a Swedish cohort of individuals with a diagnosis of trichotillomania assigned in specialist services across the country. Through the Swedish National Patient Register, we identified all individuals with an ICD-10 diagnosis of trichotillomania between January 1st, 1997 and December 31st, 2020. The cohort included 1,234 individuals, with a median age at first diagnosis of 25 years (interquartile range, 16–35). Most individuals were female (85%) and single (82%). Most (79%) individuals had a comorbid psychiatric disorder diagnosed during the study period. Anxiety-related disorders (65%), depressive disorders (48%), and neurodevelopmental disorders (39%) were the most frequent co-occurring diagnoses. Most (72%) individuals were dispensed psychotropic medications during the period ranging from 12 months prior to and 12 months after the first trichotillomania diagnosis. Antidepressants (58%), hypnotics/sedatives (36%), and anxiolytics (31%) were the most frequently dispensed medications. Altogether, the characteristics of individuals diagnosed with trichotillomania in Swedish specialist services were similar to those reported in previous literature, opening the possibility of register-based research into this underdiagnosed and understudied condition.

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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Body-focused repetitive behaviors, Disruptive, Impulse Control, and Conduct Disorders, Hair-pulling disorder, Obsessive–Compulsive disorder, Population registers
in
Scientific Reports
volume
15
issue
1
article number
10396
publisher
Nature Publishing Group
external identifiers
  • pmid:40140525
  • scopus:105000969972
ISSN
2045-2322
DOI
10.1038/s41598-025-95416-w
language
English
LU publication?
yes
id
44bccd94-4e20-43d4-989e-41641417c003
date added to LUP
2025-08-07 10:50:52
date last changed
2025-12-11 22:57:43
@article{44bccd94-4e20-43d4-989e-41641417c003,
  abstract     = {{<p>Trichotillomania is an understudied, underrecognized, and difficult-to-treat psychiatric disorder that affects about 1–2% of the population, predominantly women. This study aimed to characterize the sociodemographic and clinical characteristics of a Swedish cohort of individuals with a diagnosis of trichotillomania assigned in specialist services across the country. Through the Swedish National Patient Register, we identified all individuals with an ICD-10 diagnosis of trichotillomania between January 1<sup>st</sup>, 1997 and December 31<sup>st</sup>, 2020. The cohort included 1,234 individuals, with a median age at first diagnosis of 25 years (interquartile range, 16–35). Most individuals were female (85%) and single (82%). Most (79%) individuals had a comorbid psychiatric disorder diagnosed during the study period. Anxiety-related disorders (65%), depressive disorders (48%), and neurodevelopmental disorders (39%) were the most frequent co-occurring diagnoses. Most (72%) individuals were dispensed psychotropic medications during the period ranging from 12 months prior to and 12 months after the first trichotillomania diagnosis. Antidepressants (58%), hypnotics/sedatives (36%), and anxiolytics (31%) were the most frequently dispensed medications. Altogether, the characteristics of individuals diagnosed with trichotillomania in Swedish specialist services were similar to those reported in previous literature, opening the possibility of register-based research into this underdiagnosed and understudied condition.</p>}},
  author       = {{Farhat, Luis C. and Isomura, Kayoko and Fernández de la Cruz, Lorena and Sidorchuk, Anna and Kuja-Halkola, Ralf and Brikell, Isabell and Chang, Zheng and D’Onofrio, Brian M. and Larsson, Henrik and Lichtenstein, Paul and Mataix-Cols, David}},
  issn         = {{2045-2322}},
  keywords     = {{Body-focused repetitive behaviors; Disruptive, Impulse Control, and Conduct Disorders; Hair-pulling disorder; Obsessive–Compulsive disorder; Population registers}},
  language     = {{eng}},
  number       = {{1}},
  publisher    = {{Nature Publishing Group}},
  series       = {{Scientific Reports}},
  title        = {{Sociodemographic and clinical characteristics of 1,234 individuals diagnosed with trichotillomania in the Swedish National Patient Register}},
  url          = {{http://dx.doi.org/10.1038/s41598-025-95416-w}},
  doi          = {{10.1038/s41598-025-95416-w}},
  volume       = {{15}},
  year         = {{2025}},
}