Effects of temperature in the estimation of inhomogeneous magnetic transfer (ihMT) in post-mortem human brain
(2022) Joint Annual Meeting ISMRM-ESMRMB 2022 30.- Abstract
- Inhomogeneous magnetic transfer (ihMT) is more sensitive to myelin macromolecules than standard MT proxies. Measuring ihMT in the multi-parameter mapping protocol allows calculating ihMT from MT saturation (MTsat) maps and thus inherently correct for the undesired dependencies on flip angle and the longitudinal relaxation rate. Further validation of this new ihMT metric requires measurement of MPM-based ihMT of human post-mortem material. Here, we showed that ihMT of a whole human post-mortem brain is feasible but can lead to
temperature increase in the specimen, which is particularly pronounced in white matter.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/482af809-844e-4c85-82ee-a892a1bbcd7f
- author
- Fritz, Francisco J ; Helms, Gunther LU ; Vaculčiaková, Lenka ; Weiskopf, Nikolaus and Mohammadi, Siawoosh
- organization
- publishing date
- 2022-04-22
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- host publication
- Proceedings of the 2022 ISMRM & ISMRT Annual Meeting and Exhibition
- volume
- 30
- article number
- 2712
- publisher
- International Society for Magnetic Resonance in Medicine
- conference name
- Joint Annual Meeting ISMRM-ESMRMB 2022
- conference location
- London, United Kingdom
- conference dates
- 2022-05-07 - 2022-05-12
- language
- English
- LU publication?
- yes
- id
- 482af809-844e-4c85-82ee-a892a1bbcd7f
- alternative location
- https://index.mirasmart.com/ISMRM2022/PDFfiles/2712.html
- date added to LUP
- 2022-02-07 14:46:57
- date last changed
- 2022-11-29 08:06:04
@inproceedings{482af809-844e-4c85-82ee-a892a1bbcd7f, abstract = {{Inhomogeneous magnetic transfer (ihMT) is more sensitive to myelin macromolecules than standard MT proxies. Measuring ihMT in the multi-parameter mapping protocol allows calculating ihMT from MT saturation (MTsat) maps and thus inherently correct for the undesired dependencies on flip angle and the longitudinal relaxation rate. Further validation of this new ihMT metric requires measurement of MPM-based ihMT of human post-mortem material. Here, we showed that ihMT of a whole human post-mortem brain is feasible but can lead to<br/>temperature increase in the specimen, which is particularly pronounced in white matter.<br/>}}, author = {{Fritz, Francisco J and Helms, Gunther and Vaculčiaková, Lenka and Weiskopf, Nikolaus and Mohammadi, Siawoosh}}, booktitle = {{Proceedings of the 2022 ISMRM & ISMRT Annual Meeting and Exhibition}}, language = {{eng}}, month = {{04}}, publisher = {{International Society for Magnetic Resonance in Medicine}}, title = {{Effects of temperature in the estimation of inhomogeneous magnetic transfer (ihMT) in post-mortem human brain}}, url = {{https://index.mirasmart.com/ISMRM2022/PDFfiles/2712.html}}, volume = {{30}}, year = {{2022}}, }