Single-distance nano-holotomography with coded apertures
(2025) In Optics Letters 50(2). p.574-577- Abstract
High-resolution phase-contrast 3D imaging using nano-holotomography typically requires collecting multiple tomograms at varying sample-to-detector distances, usually 3 to 4. This multi-distance approach limits temporal resolution, making it impractical for operando studies. Moreover, shifting the sample complicates reconstruction, requiring precise alignment, registration, and interpolation to correct for shift-dependent magnification on the detector. In response, we propose and validate through simulations a novel, to the best of our knowledge, single-distance approach that leverages coded apertures to structure beam illumination while the sample rotates. This approach relies on a joint reconstruction scheme, which integrates phase... (More)
High-resolution phase-contrast 3D imaging using nano-holotomography typically requires collecting multiple tomograms at varying sample-to-detector distances, usually 3 to 4. This multi-distance approach limits temporal resolution, making it impractical for operando studies. Moreover, shifting the sample complicates reconstruction, requiring precise alignment, registration, and interpolation to correct for shift-dependent magnification on the detector. In response, we propose and validate through simulations a novel, to the best of our knowledge, single-distance approach that leverages coded apertures to structure beam illumination while the sample rotates. This approach relies on a joint reconstruction scheme, which integrates phase retrieval with 3D tomography, ensuring data consistency and achieving artifact-free reconstructions from a single distance, unlocking dynamic experiments.
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- author
- Nikitin, Viktor LU ; Carlsson, Marcus LU ; Mokso, Rajmund LU ; Cloetens, Peter and Gürsoy, Doğa
- organization
- publishing date
- 2025-01
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Optics Letters
- volume
- 50
- issue
- 2
- pages
- 4 pages
- publisher
- Optical Society of America
- external identifiers
-
- pmid:39815565
- scopus:85215957232
- ISSN
- 0146-9592
- DOI
- 10.1364/OL.541765
- language
- English
- LU publication?
- yes
- id
- 482bec77-2a87-4c27-9754-54f5e13ebc30
- date added to LUP
- 2026-01-09 14:44:42
- date last changed
- 2026-01-09 14:45:16
@article{482bec77-2a87-4c27-9754-54f5e13ebc30,
abstract = {{<p>High-resolution phase-contrast 3D imaging using nano-holotomography typically requires collecting multiple tomograms at varying sample-to-detector distances, usually 3 to 4. This multi-distance approach limits temporal resolution, making it impractical for operando studies. Moreover, shifting the sample complicates reconstruction, requiring precise alignment, registration, and interpolation to correct for shift-dependent magnification on the detector. In response, we propose and validate through simulations a novel, to the best of our knowledge, single-distance approach that leverages coded apertures to structure beam illumination while the sample rotates. This approach relies on a joint reconstruction scheme, which integrates phase retrieval with 3D tomography, ensuring data consistency and achieving artifact-free reconstructions from a single distance, unlocking dynamic experiments.</p>}},
author = {{Nikitin, Viktor and Carlsson, Marcus and Mokso, Rajmund and Cloetens, Peter and Gürsoy, Doğa}},
issn = {{0146-9592}},
language = {{eng}},
number = {{2}},
pages = {{574--577}},
publisher = {{Optical Society of America}},
series = {{Optics Letters}},
title = {{Single-distance nano-holotomography with coded apertures}},
url = {{http://dx.doi.org/10.1364/OL.541765}},
doi = {{10.1364/OL.541765}},
volume = {{50}},
year = {{2025}},
}