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Trimodal low-dose X-ray tomography

Zanette, I. ; Bech, M. LU orcid ; Rack, A. ; Le Duc, G. ; Tafforeau, P. ; David, C. ; Mohr, J. ; Pfeiffer, F. and Weitkamp, T. (2012) In Proceedings of the National Academy of Sciences of the United States of America 109(26). p.10199-10204
Abstract

X-ray grating interferometry is a coherent imaging technique that bears tremendous potential for three-dimensional tomographic imaging of soft biological tissue and other specimens whose details exhibit very weak absorption contrast. It is intrinsically trimodal, delivering phase contrast, absorption contrast, and scattering ("dark-field") contrast. Recently reported acquisition strategies for grating-interferometric phase tomography constitute a major improvement of dose efficiency and speed. In particular, some of these techniques eliminate the need for scanning of one of the gratings ("phase stepping"). This advantage, however, comes at the cost of other limitations. These can be a loss in spatial resolution, or the inability to... (More)

X-ray grating interferometry is a coherent imaging technique that bears tremendous potential for three-dimensional tomographic imaging of soft biological tissue and other specimens whose details exhibit very weak absorption contrast. It is intrinsically trimodal, delivering phase contrast, absorption contrast, and scattering ("dark-field") contrast. Recently reported acquisition strategies for grating-interferometric phase tomography constitute a major improvement of dose efficiency and speed. In particular, some of these techniques eliminate the need for scanning of one of the gratings ("phase stepping"). This advantage, however, comes at the cost of other limitations. These can be a loss in spatial resolution, or the inability to fully separate the three imaging modalities. In the present paper we report a data acquisition and processing method that optimizes dose efficiency but does not share the main limitations of other recently reported methods. Although our method still relies on phase stepping, it effectively uses only down to a single detector frame per projection angle and yields images corresponding to all three contrast modalities. In particular, this means that dark-field imaging remains accessible. The method is also compliant with data acquisition over an angular range of only 180° and with a continuous rotation of the specimen.

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author
; ; ; ; ; ; ; and
publishing date
type
Contribution to journal
publication status
published
keywords
Paleontology, X-ray dark-field imaging, X-ray medical imaging, X-ray microtomography, X-ray phase-contrast imaging
in
Proceedings of the National Academy of Sciences of the United States of America
volume
109
issue
26
pages
10199 - 10204
publisher
National Academy of Sciences
external identifiers
  • pmid:22699500
  • scopus:84862977187
ISSN
0027-8424
DOI
10.1073/pnas.1117861109
language
English
LU publication?
no
id
485b39d9-dc77-4cc5-96b8-6e6163f14562
date added to LUP
2022-04-07 11:14:55
date last changed
2025-04-12 15:50:38
@article{485b39d9-dc77-4cc5-96b8-6e6163f14562,
  abstract     = {{<p>X-ray grating interferometry is a coherent imaging technique that bears tremendous potential for three-dimensional tomographic imaging of soft biological tissue and other specimens whose details exhibit very weak absorption contrast. It is intrinsically trimodal, delivering phase contrast, absorption contrast, and scattering ("dark-field") contrast. Recently reported acquisition strategies for grating-interferometric phase tomography constitute a major improvement of dose efficiency and speed. In particular, some of these techniques eliminate the need for scanning of one of the gratings ("phase stepping"). This advantage, however, comes at the cost of other limitations. These can be a loss in spatial resolution, or the inability to fully separate the three imaging modalities. In the present paper we report a data acquisition and processing method that optimizes dose efficiency but does not share the main limitations of other recently reported methods. Although our method still relies on phase stepping, it effectively uses only down to a single detector frame per projection angle and yields images corresponding to all three contrast modalities. In particular, this means that dark-field imaging remains accessible. The method is also compliant with data acquisition over an angular range of only 180° and with a continuous rotation of the specimen.</p>}},
  author       = {{Zanette, I. and Bech, M. and Rack, A. and Le Duc, G. and Tafforeau, P. and David, C. and Mohr, J. and Pfeiffer, F. and Weitkamp, T.}},
  issn         = {{0027-8424}},
  keywords     = {{Paleontology; X-ray dark-field imaging; X-ray medical imaging; X-ray microtomography; X-ray phase-contrast imaging}},
  language     = {{eng}},
  number       = {{26}},
  pages        = {{10199--10204}},
  publisher    = {{National Academy of Sciences}},
  series       = {{Proceedings of the National Academy of Sciences of the United States of America}},
  title        = {{Trimodal low-dose X-ray tomography}},
  url          = {{http://dx.doi.org/10.1073/pnas.1117861109}},
  doi          = {{10.1073/pnas.1117861109}},
  volume       = {{109}},
  year         = {{2012}},
}