Myeloid-related protein 14 promote inflammation and injury in meningitis.
(2015) In Journal of Infectious Diseases 212(2). p.247-257- Abstract
- Neutrophilic inflammation often persists over days despite efficient antibiotic treatment and contributes to brain damage in bacterial meningitis. We proposed here that MRP14, an abundant cytosolic protein in myeloid cells, acts as an endogenous danger signal, driving inflammation and aggravating tissue injury.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/5040077
- author
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Infectious Diseases
- volume
- 212
- issue
- 2
- pages
- 247 - 257
- publisher
- Oxford University Press
- external identifiers
-
- pmid:25605866
- wos:000357823300010
- scopus:84936867554
- pmid:25605866
- ISSN
- 1537-6613
- DOI
- 10.1093/infdis/jiv028
- language
- English
- LU publication?
- yes
- id
- bb5ca0c7-3186-4c7a-b19e-4ef194dc5c8e (old id 5040077)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/25605866?dopt=Abstract
- date added to LUP
- 2016-04-01 10:00:21
- date last changed
- 2022-04-27 17:40:19
@article{bb5ca0c7-3186-4c7a-b19e-4ef194dc5c8e, abstract = {{Neutrophilic inflammation often persists over days despite efficient antibiotic treatment and contributes to brain damage in bacterial meningitis. We proposed here that MRP14, an abundant cytosolic protein in myeloid cells, acts as an endogenous danger signal, driving inflammation and aggravating tissue injury.}}, author = {{Wache, Christina and Klein, Matthias and Ostergaard, Christian and Angele, Barbara and Häcker, Hans and Pfister, Hans-Walter and Pruenster, Monika and Sperandio, Markus and Leanderson, Tomas and Roth, Johannes and Vogl, Thomas and Koedel, Uwe}}, issn = {{1537-6613}}, language = {{eng}}, number = {{2}}, pages = {{247--257}}, publisher = {{Oxford University Press}}, series = {{Journal of Infectious Diseases}}, title = {{Myeloid-related protein 14 promote inflammation and injury in meningitis.}}, url = {{http://dx.doi.org/10.1093/infdis/jiv028}}, doi = {{10.1093/infdis/jiv028}}, volume = {{212}}, year = {{2015}}, }