The risk for depression in patients with ankylosing spondylitis: a population-based cohort study
Meesters, Jorit J. L. ; Bremander, Ann LU ; Bergman, Stefan LU ; Petersson, Ingemar LU ; Turkiewicz, Aleksandra LU and Englund, Martin LU
(2014)
In Arthritis Research and Therapy
16(418).
p.1-5
- Abstract
- Introduction: Depression is frequent in ankylosing spondylitis (AS) patients. However, epidemiological data about the potential increase in risk are lacking. This study compares the rate of doctor-diagnosed depression in a well defined cohort of AS patients to the general population seeking care. Methods: The Skane Healthcare Register comprises healthcare data of each resident in Region Skane, Sweden (population 1.2 million), including ICD-10 diagnoses. Using physician coded consultation data from years 1999 to 2011, we calculated depression consultation rates for all AS patients. We obtained standardized depression-rate ratios by dividing the observed depression rate in AS patients by the expected rate based on the corresponding age-and... (More)
- Introduction: Depression is frequent in ankylosing spondylitis (AS) patients. However, epidemiological data about the potential increase in risk are lacking. This study compares the rate of doctor-diagnosed depression in a well defined cohort of AS patients to the general population seeking care. Methods: The Skane Healthcare Register comprises healthcare data of each resident in Region Skane, Sweden (population 1.2 million), including ICD-10 diagnoses. Using physician coded consultation data from years 1999 to 2011, we calculated depression consultation rates for all AS patients. We obtained standardized depression-rate ratios by dividing the observed depression rate in AS patients by the expected rate based on the corresponding age-and sex-specific rates of depression in the general population seeking care. A ratio > 1 equals a higher rate of depression among AS patients. Results: The AS cohort consisted of 1738 subjects (65% men) with a mean age of 54 years. The reference population consisted of 967,012 subjects. During the 13-year observation period 10% (n = 172) of the AS cohort had a doctor-diagnosed depression compared to 6% (n = 105) to be expected. The standardized estimate of depression-rate ratio was 1.81 (95% confidence interval 1.44 to 2.24) in women men and 1.49 (1.20 to 1.89) in men. Conclusions: The rate of doctor-diagnosed depression is increased about 80% in female and 50% in male AS patients. Future challenges are to timely identify and treat the AS patients who suffer from depression. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/5185962
- author
- Meesters, Jorit J. L.
; Bremander, Ann
LU
; Bergman, Stefan
LU
; Petersson, Ingemar
LU
; Turkiewicz, Aleksandra
LU
and Englund, Martin
LU
- organization
- publishing date
- 2014
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Arthritis Research and Therapy
- volume
- 16
- issue
- 418
- pages
- 1 - 5
- publisher
- BioMed Central (BMC)
- external identifiers
-
- wos:000349885900003
- scopus:84910037660
- pmid:25209603
- ISSN
- 1478-6362
- DOI
- 10.1186/s13075-014-0418-z
- language
- English
- LU publication?
- yes
- id
- b6aa1008-319b-423c-a7da-a7a150ecd2f5 (old id 5185962)
- date added to LUP
- 2016-04-01 10:41:08
- date last changed
- 2022-02-17 20:21:45
@article{b6aa1008-319b-423c-a7da-a7a150ecd2f5,
abstract = {{Introduction: Depression is frequent in ankylosing spondylitis (AS) patients. However, epidemiological data about the potential increase in risk are lacking. This study compares the rate of doctor-diagnosed depression in a well defined cohort of AS patients to the general population seeking care. Methods: The Skane Healthcare Register comprises healthcare data of each resident in Region Skane, Sweden (population 1.2 million), including ICD-10 diagnoses. Using physician coded consultation data from years 1999 to 2011, we calculated depression consultation rates for all AS patients. We obtained standardized depression-rate ratios by dividing the observed depression rate in AS patients by the expected rate based on the corresponding age-and sex-specific rates of depression in the general population seeking care. A ratio > 1 equals a higher rate of depression among AS patients. Results: The AS cohort consisted of 1738 subjects (65% men) with a mean age of 54 years. The reference population consisted of 967,012 subjects. During the 13-year observation period 10% (n = 172) of the AS cohort had a doctor-diagnosed depression compared to 6% (n = 105) to be expected. The standardized estimate of depression-rate ratio was 1.81 (95% confidence interval 1.44 to 2.24) in women men and 1.49 (1.20 to 1.89) in men. Conclusions: The rate of doctor-diagnosed depression is increased about 80% in female and 50% in male AS patients. Future challenges are to timely identify and treat the AS patients who suffer from depression.}},
author = {{Meesters, Jorit J. L. and Bremander, Ann and Bergman, Stefan and Petersson, Ingemar and Turkiewicz, Aleksandra and Englund, Martin}},
issn = {{1478-6362}},
language = {{eng}},
number = {{418}},
pages = {{1--5}},
publisher = {{BioMed Central (BMC)}},
series = {{Arthritis Research and Therapy}},
title = {{The risk for depression in patients with ankylosing spondylitis: a population-based cohort study}},
url = {{https://lup.lub.lu.se/search/files/2052200/7985087}},
doi = {{10.1186/s13075-014-0418-z}},
volume = {{16}},
year = {{2014}},
}