The role of Fusobacterium necrophorum in pharyngotonsillitis – A review
(2016) In Anaerobe 42. p.89-97- Abstract
Fusobacterium necrophorum is a gram-negative anaerobic bacterium that is the causative agent of the invasive disease Lemierre's syndrome. In addition, it is also associated with peritonsillar abscess formation and otitis media in small children. Recent research has shown that F. necrophorum may be involved in pharyngotonsillitis especially in adolescent and young adults and that it may be the second most common bacterial cause of pharyngotonsillitis after Streptococcus pyogenes (Group A streptococci). Peritonsillar abscesses and Lemierre's syndrome due to F. necrophorum are also found in this age group, suggesting that they may be complications of F. necrophorum pharyngotonsillitis. In this review we present the present knowledge about... (More)
Fusobacterium necrophorum is a gram-negative anaerobic bacterium that is the causative agent of the invasive disease Lemierre's syndrome. In addition, it is also associated with peritonsillar abscess formation and otitis media in small children. Recent research has shown that F. necrophorum may be involved in pharyngotonsillitis especially in adolescent and young adults and that it may be the second most common bacterial cause of pharyngotonsillitis after Streptococcus pyogenes (Group A streptococci). Peritonsillar abscesses and Lemierre's syndrome due to F. necrophorum are also found in this age group, suggesting that they may be complications of F. necrophorum pharyngotonsillitis. In this review we present the present knowledge about the role of F. necrophorum in pharyngotonsillitis with special emphasis on the age distribution. We argue that F. necrophorum is an important pathogen involved in pharyngotonsillitis in the age group of 13–40 years of age and we urge clinical microbiology labs to set up the appropriate techniques to be able to detect F. necrophorum from throat swabs.
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- author
- Holm, Karin LU ; Bank, Steffen ; Nielsen, Hanne ; Kristensen, Lena Hagelskjær ; Prag, Jørgen and Jensen, Anders
- organization
- publishing date
- 2016-12
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Fusobacterium necrophorum, Lemierre, Lemierre's syndrome, Peritonsillar abscess, Pharyngitis, Pharyngotonsillitis, Tonsillitis
- in
- Anaerobe
- volume
- 42
- pages
- 89 - 97
- publisher
- Elsevier
- external identifiers
-
- scopus:84988910367
- pmid:27693542
- wos:000390628600017
- ISSN
- 1075-9964
- DOI
- 10.1016/j.anaerobe.2016.09.006
- language
- English
- LU publication?
- yes
- id
- 52cfbad5-8329-414a-9a0d-e569018ceacf
- date added to LUP
- 2016-10-12 13:40:11
- date last changed
- 2024-07-27 20:07:57
@article{52cfbad5-8329-414a-9a0d-e569018ceacf, abstract = {{<p>Fusobacterium necrophorum is a gram-negative anaerobic bacterium that is the causative agent of the invasive disease Lemierre's syndrome. In addition, it is also associated with peritonsillar abscess formation and otitis media in small children. Recent research has shown that F. necrophorum may be involved in pharyngotonsillitis especially in adolescent and young adults and that it may be the second most common bacterial cause of pharyngotonsillitis after Streptococcus pyogenes (Group A streptococci). Peritonsillar abscesses and Lemierre's syndrome due to F. necrophorum are also found in this age group, suggesting that they may be complications of F. necrophorum pharyngotonsillitis. In this review we present the present knowledge about the role of F. necrophorum in pharyngotonsillitis with special emphasis on the age distribution. We argue that F. necrophorum is an important pathogen involved in pharyngotonsillitis in the age group of 13–40 years of age and we urge clinical microbiology labs to set up the appropriate techniques to be able to detect F. necrophorum from throat swabs.</p>}}, author = {{Holm, Karin and Bank, Steffen and Nielsen, Hanne and Kristensen, Lena Hagelskjær and Prag, Jørgen and Jensen, Anders}}, issn = {{1075-9964}}, keywords = {{Fusobacterium necrophorum; Lemierre; Lemierre's syndrome; Peritonsillar abscess; Pharyngitis; Pharyngotonsillitis; Tonsillitis}}, language = {{eng}}, pages = {{89--97}}, publisher = {{Elsevier}}, series = {{Anaerobe}}, title = {{The role of Fusobacterium necrophorum in pharyngotonsillitis – A review}}, url = {{http://dx.doi.org/10.1016/j.anaerobe.2016.09.006}}, doi = {{10.1016/j.anaerobe.2016.09.006}}, volume = {{42}}, year = {{2016}}, }