Drug delivery to retinal photoreceptors
(2019) In Drug Discovery Today 24(8). p.1637-1643- Abstract
The photoreceptors of the retina are afflicted by diseases that still often lack satisfactory treatment options. Although suitable drugs might be available in some cases, the delivery of these compounds into the eye and across the blood–retinal barrier remains a significant challenge for therapy development. Here, we review the routes of drug administration to the retina and highlight different options for drug delivery to the photoreceptor cells.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/532c8f82-77c5-459b-b742-4852073780bc
- author
- Himawan, Erico ; Ekström, Per LU ; Buzgo, Matej ; Gaillard, Pieter ; Stefánsson, Einar ; Marigo, Valeria ; Loftsson, Thorsteinn and Paquet-Durand, François LU
- organization
- publishing date
- 2019
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Drug Discovery Today
- volume
- 24
- issue
- 8
- pages
- 1637 - 1643
- publisher
- Elsevier
- external identifiers
-
- scopus:85063296590
- pmid:30877076
- ISSN
- 1359-6446
- DOI
- 10.1016/j.drudis.2019.03.004
- language
- English
- LU publication?
- yes
- id
- 532c8f82-77c5-459b-b742-4852073780bc
- date added to LUP
- 2019-04-08 13:16:51
- date last changed
- 2025-02-05 08:08:54
@article{532c8f82-77c5-459b-b742-4852073780bc, abstract = {{<p>The photoreceptors of the retina are afflicted by diseases that still often lack satisfactory treatment options. Although suitable drugs might be available in some cases, the delivery of these compounds into the eye and across the blood–retinal barrier remains a significant challenge for therapy development. Here, we review the routes of drug administration to the retina and highlight different options for drug delivery to the photoreceptor cells.</p>}}, author = {{Himawan, Erico and Ekström, Per and Buzgo, Matej and Gaillard, Pieter and Stefánsson, Einar and Marigo, Valeria and Loftsson, Thorsteinn and Paquet-Durand, François}}, issn = {{1359-6446}}, language = {{eng}}, number = {{8}}, pages = {{1637--1643}}, publisher = {{Elsevier}}, series = {{Drug Discovery Today}}, title = {{Drug delivery to retinal photoreceptors}}, url = {{http://dx.doi.org/10.1016/j.drudis.2019.03.004}}, doi = {{10.1016/j.drudis.2019.03.004}}, volume = {{24}}, year = {{2019}}, }