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Regional assessment of availability for transcatheter aortic valve implantation in Sweden : a long-term observational study

Nilsson, Konrad ; Lindholm, Daniel ; Backes, Jenny ; Bjursten, Henrik LU ; Hagström, Henrik ; Lindbäck, Johan ; Pétursson, Pétur ; Settergren, Magnus ; Sarno, Giovanna and James, Stefan (2024) In European Heart Journal - Quality of Care and Clinical Outcomes 10(7). p.641-649
Abstract

Background Transcatheter aortic valve implantation (TAVI) is an increasingly important treatment option for patients with severe aortic stenosis. Its best implementation is debated, as few centres with high volumes are associated with better outcomes, while centralization might lead to an inferior availability of treatment for patients living far away. The aim of this study was to investigate the implementation of TAVI in Sweden with a focus on regional differences in terms of availability, short-term mortality, and waiting times. Methods All patients undergoing TAVI between 2008 and 2020 from the Swedish Transcatheter Cardiac Intervention Registry (SWENTRY) were included. SWENTRY was linked to the National Cause of Death Registry and... (More)

Background Transcatheter aortic valve implantation (TAVI) is an increasingly important treatment option for patients with severe aortic stenosis. Its best implementation is debated, as few centres with high volumes are associated with better outcomes, while centralization might lead to an inferior availability of treatment for patients living far away. The aim of this study was to investigate the implementation of TAVI in Sweden with a focus on regional differences in terms of availability, short-term mortality, and waiting times. Methods All patients undergoing TAVI between 2008 and 2020 from the Swedish Transcatheter Cardiac Intervention Registry (SWENTRY) were included. SWENTRY was linked to the National Cause of Death Registry and to publicly available geospatial data from Statistics Sweden. Results A total of 7280 patients were included. Over time, TAVI interventions increased markedly, while surgical aortic valve replacement (SAVR) remained constant. There were no statistically significant regional differences in incidence between counties with or without a local TAVI centre (P = 0.7) and no clustering tendencies around regions with a local TAVI centre (P = 0.99). Thirty-day mortality improved over time without evidence of regional differences. No regional differences in waiting time from decision to intervention were found for TAVI centre regions and non-TAVI centre regions (P = 0.7). Conclusion This nationwide study indicated no regional differences in terms of availability, short-term mortality, or waiting times. An organization with a few specialized centres was found to be sufficient to provide national coverage of TAVI interventions.

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; ; ; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Aortic stenosis, Equal care, Implementation Health care organisation, Transcatheter aortic valve implantation
in
European Heart Journal - Quality of Care and Clinical Outcomes
volume
10
issue
7
pages
641 - 649
publisher
Oxford University Press
external identifiers
  • pmid:38158216
  • scopus:85208658268
ISSN
2058-5225
DOI
10.1093/ehjqcco/qcad076
language
English
LU publication?
yes
additional info
Publisher Copyright: © The Author(s) 2023. Published by Oxford University Press on behalf of the European Society of Cardiology.
id
54f5a476-1185-45f3-bda7-627873d907a3
date added to LUP
2024-12-01 16:40:18
date last changed
2025-01-26 21:29:08
@article{54f5a476-1185-45f3-bda7-627873d907a3,
  abstract     = {{<p>Background Transcatheter aortic valve implantation (TAVI) is an increasingly important treatment option for patients with severe aortic stenosis. Its best implementation is debated, as few centres with high volumes are associated with better outcomes, while centralization might lead to an inferior availability of treatment for patients living far away. The aim of this study was to investigate the implementation of TAVI in Sweden with a focus on regional differences in terms of availability, short-term mortality, and waiting times. Methods All patients undergoing TAVI between 2008 and 2020 from the Swedish Transcatheter Cardiac Intervention Registry (SWENTRY) were included. SWENTRY was linked to the National Cause of Death Registry and to publicly available geospatial data from Statistics Sweden. Results A total of 7280 patients were included. Over time, TAVI interventions increased markedly, while surgical aortic valve replacement (SAVR) remained constant. There were no statistically significant regional differences in incidence between counties with or without a local TAVI centre (P = 0.7) and no clustering tendencies around regions with a local TAVI centre (P = 0.99). Thirty-day mortality improved over time without evidence of regional differences. No regional differences in waiting time from decision to intervention were found for TAVI centre regions and non-TAVI centre regions (P = 0.7). Conclusion This nationwide study indicated no regional differences in terms of availability, short-term mortality, or waiting times. An organization with a few specialized centres was found to be sufficient to provide national coverage of TAVI interventions.</p>}},
  author       = {{Nilsson, Konrad and Lindholm, Daniel and Backes, Jenny and Bjursten, Henrik and Hagström, Henrik and Lindbäck, Johan and Pétursson, Pétur and Settergren, Magnus and Sarno, Giovanna and James, Stefan}},
  issn         = {{2058-5225}},
  keywords     = {{Aortic stenosis; Equal care; Implementation Health care organisation; Transcatheter aortic valve implantation}},
  language     = {{eng}},
  month        = {{11}},
  number       = {{7}},
  pages        = {{641--649}},
  publisher    = {{Oxford University Press}},
  series       = {{European Heart Journal - Quality of Care and Clinical Outcomes}},
  title        = {{Regional assessment of availability for transcatheter aortic valve implantation in Sweden : a long-term observational study}},
  url          = {{http://dx.doi.org/10.1093/ehjqcco/qcad076}},
  doi          = {{10.1093/ehjqcco/qcad076}},
  volume       = {{10}},
  year         = {{2024}},
}