Perineal Groove : An Anorectal Malformation Network, Consortium Study
Samuk, Inbal ; Amerstorfer, Eva E. ; Fanjul, Maria ; Iacobelli, Barbara D. ; Lisi, Gabriele ; Midrio, Paola ; Morandi, Anna ; Schmiedeke, Eberhard ; Stenstrom, Pernilla LU
and Sleeboom, Christien
(2020)
In Journal of Pediatrics
222.
p.207-212
- Abstract
Objective: To review the Anorectal Malformation Network experience with perineal groove (PG) focusing on its clinical characteristics and management. Study design: Data on patients with PG managed at 10 participating Anorectal Malformation Network centers in 1999-2019 were collected retrospectively by questionnaire. Results: The cohort included 66 patients (65 females) of median age 1.4 months at diagnosis. The leading referral diagnosis was anal fissure (n = 20 [30.3%]): 23 patients (34.8%) had anorectal malformations. Expectant management was practiced in 47 patients (71.2%). Eight (17%) were eventually operated for local complications. The median time to surgery was 14 months (range, 3.0-48.6 months), and the median age at surgery... (More)
Objective: To review the Anorectal Malformation Network experience with perineal groove (PG) focusing on its clinical characteristics and management. Study design: Data on patients with PG managed at 10 participating Anorectal Malformation Network centers in 1999-2019 were collected retrospectively by questionnaire. Results: The cohort included 66 patients (65 females) of median age 1.4 months at diagnosis. The leading referral diagnosis was anal fissure (n = 20 [30.3%]): 23 patients (34.8%) had anorectal malformations. Expectant management was practiced in 47 patients (71.2%). Eight (17%) were eventually operated for local complications. The median time to surgery was 14 months (range, 3.0-48.6 months), and the median age at surgery was 18.3 months (range, 4.8-58.0 months). In the 35 patients available for follow-up of the remaining 39 managed expectantly, 23 (65.7%) showed complete or near-complete self-epithelization by a mean age 15.3 months (range, 1-72 months) and 4 (11.4%) showed partial self-epithelization by a mean age 21 months (range, 3-48 months). Eight patients showed no resolution (5 were followed for ≤3 months). Nineteen patients (28.7%) were primarily treated with surgery. In total, 27 patients were operated. Dehiscence occurred in 3 of 27 operated patients (11.1%). Conclusions: PG seems to be an underestimated anomaly, frequently associated with anorectal malformations. Most cases heal spontaneously; therefore, expectant management is recommended. When associated with anorectal malformations requiring reconstruction, PG should be excised in conjunction with the anorectoplasty.
(Less)
- author
- Samuk, Inbal
; Amerstorfer, Eva E.
; Fanjul, Maria
; Iacobelli, Barbara D.
; Lisi, Gabriele
; Midrio, Paola
; Morandi, Anna
; Schmiedeke, Eberhard
; Stenstrom, Pernilla
LU
and Sleeboom, Christien
- organization
- publishing date
- 2020
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- anorectal malformations, congenital anomaly, groove, neonatal, perineal sulcus, perineum
- in
- Journal of Pediatrics
- volume
- 222
- pages
- 6 pages
- publisher
- Academic Press
- external identifiers
-
- pmid:32586525
- scopus:85086589220
- ISSN
- 0022-3476
- DOI
- 10.1016/j.jpeds.2020.03.026
- language
- English
- LU publication?
- yes
- id
- 58cfab15-4eb0-400e-98c0-8d154c3f55a1
- date added to LUP
- 2020-07-02 12:42:12
- date last changed
- 2024-04-17 11:18:55
@article{58cfab15-4eb0-400e-98c0-8d154c3f55a1,
abstract = {{<p>Objective: To review the Anorectal Malformation Network experience with perineal groove (PG) focusing on its clinical characteristics and management. Study design: Data on patients with PG managed at 10 participating Anorectal Malformation Network centers in 1999-2019 were collected retrospectively by questionnaire. Results: The cohort included 66 patients (65 females) of median age 1.4 months at diagnosis. The leading referral diagnosis was anal fissure (n = 20 [30.3%]): 23 patients (34.8%) had anorectal malformations. Expectant management was practiced in 47 patients (71.2%). Eight (17%) were eventually operated for local complications. The median time to surgery was 14 months (range, 3.0-48.6 months), and the median age at surgery was 18.3 months (range, 4.8-58.0 months). In the 35 patients available for follow-up of the remaining 39 managed expectantly, 23 (65.7%) showed complete or near-complete self-epithelization by a mean age 15.3 months (range, 1-72 months) and 4 (11.4%) showed partial self-epithelization by a mean age 21 months (range, 3-48 months). Eight patients showed no resolution (5 were followed for ≤3 months). Nineteen patients (28.7%) were primarily treated with surgery. In total, 27 patients were operated. Dehiscence occurred in 3 of 27 operated patients (11.1%). Conclusions: PG seems to be an underestimated anomaly, frequently associated with anorectal malformations. Most cases heal spontaneously; therefore, expectant management is recommended. When associated with anorectal malformations requiring reconstruction, PG should be excised in conjunction with the anorectoplasty.</p>}},
author = {{Samuk, Inbal and Amerstorfer, Eva E. and Fanjul, Maria and Iacobelli, Barbara D. and Lisi, Gabriele and Midrio, Paola and Morandi, Anna and Schmiedeke, Eberhard and Stenstrom, Pernilla and Sleeboom, Christien}},
issn = {{0022-3476}},
keywords = {{anorectal malformations; congenital anomaly; groove; neonatal; perineal sulcus; perineum}},
language = {{eng}},
pages = {{207--212}},
publisher = {{Academic Press}},
series = {{Journal of Pediatrics}},
title = {{Perineal Groove : An Anorectal Malformation Network, Consortium Study}},
url = {{http://dx.doi.org/10.1016/j.jpeds.2020.03.026}},
doi = {{10.1016/j.jpeds.2020.03.026}},
volume = {{222}},
year = {{2020}},
}