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Ophthalmological outcome of 6.5 years children treated for retinopathy of prematurity : A Swedish register study

Larsson, Eva ; Hellström, Ann LU ; Tornqvist, Kristina LU ; Wallin, Agneta ; Sunnqvist, Birgitta ; Sandgren Hochhard, Karin ; Lundgren, Pia ; Al-Hawasi, Abbas ; Teär Fahnehjelm, Kristina and Gränse, Lotta LU orcid , et al. (2024) In British Journal of Ophthalmology 108(1). p.137-142
Abstract

Aims: To determine the ophthalmological outcome at 6.5 years of age in children treated for retinopathy of prematurity (ROP), and registered in the national Swedish National Register for ROP register. Methods: Data on ROP, treatment and ophthalmological outcome were retrieved from the register. Visual acuity (VA), refractive errors and strabismus, together with visual impairment (VI) and any significant eye problem, defined as VA >0.5 logarithm of the minimal angle of resolution (logMAR) and/or strabismus and/or any refractive error were analysed. Risk factors such as sex, gestational age (GA), birth weight SD score, number of treatments and retreatments, postnatal age and postmenstrual age at first treatment were analysed. Results:... (More)

Aims: To determine the ophthalmological outcome at 6.5 years of age in children treated for retinopathy of prematurity (ROP), and registered in the national Swedish National Register for ROP register. Methods: Data on ROP, treatment and ophthalmological outcome were retrieved from the register. Visual acuity (VA), refractive errors and strabismus, together with visual impairment (VI) and any significant eye problem, defined as VA >0.5 logarithm of the minimal angle of resolution (logMAR) and/or strabismus and/or any refractive error were analysed. Risk factors such as sex, gestational age (GA), birth weight SD score, number of treatments and retreatments, postnatal age and postmenstrual age at first treatment were analysed. Results: Follow-up data were available in 232 of 270 children born between 2007 and 2014 who had been treated for ROP. VI (VA >0.5 logMAR) was found in 32 (14%), strabismus in 82 (38%), refractive errors in 114 (52%) and significant eye problem in 143 (65%) children. Retreatment was a risk factor for VI and refractive errors. Male sex and neonatal brain lesion were risk factors for strabismus. An additional week of GA at birth reduced the risk for refractive errors, strabismus and significant eye problems. Conclusion: The results of the present study revealed a high number of eye problems in children treated for ROP, emphasising the need for long-term follow-up. Retreatment of ROP was a risk factor for VI, and emphasises the importance of an accurate first treatment for the long-term ophthalmological outcome.

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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
child health (paediatrics), epidemiology, retina, treatment other, vision
in
British Journal of Ophthalmology
volume
108
issue
1
pages
137 - 142
publisher
BMJ Publishing Group
external identifiers
  • scopus:85148666150
  • pmid:36717199
ISSN
0007-1161
DOI
10.1136/bjo-2022-322022
language
English
LU publication?
yes
id
59b99f11-b234-4c98-a20b-eb7af16a9bfb
date added to LUP
2023-03-20 10:14:18
date last changed
2024-07-12 03:02:10
@article{59b99f11-b234-4c98-a20b-eb7af16a9bfb,
  abstract     = {{<p>Aims: To determine the ophthalmological outcome at 6.5 years of age in children treated for retinopathy of prematurity (ROP), and registered in the national Swedish National Register for ROP register. Methods: Data on ROP, treatment and ophthalmological outcome were retrieved from the register. Visual acuity (VA), refractive errors and strabismus, together with visual impairment (VI) and any significant eye problem, defined as VA &gt;0.5 logarithm of the minimal angle of resolution (logMAR) and/or strabismus and/or any refractive error were analysed. Risk factors such as sex, gestational age (GA), birth weight SD score, number of treatments and retreatments, postnatal age and postmenstrual age at first treatment were analysed. Results: Follow-up data were available in 232 of 270 children born between 2007 and 2014 who had been treated for ROP. VI (VA &gt;0.5 logMAR) was found in 32 (14%), strabismus in 82 (38%), refractive errors in 114 (52%) and significant eye problem in 143 (65%) children. Retreatment was a risk factor for VI and refractive errors. Male sex and neonatal brain lesion were risk factors for strabismus. An additional week of GA at birth reduced the risk for refractive errors, strabismus and significant eye problems. Conclusion: The results of the present study revealed a high number of eye problems in children treated for ROP, emphasising the need for long-term follow-up. Retreatment of ROP was a risk factor for VI, and emphasises the importance of an accurate first treatment for the long-term ophthalmological outcome.</p>}},
  author       = {{Larsson, Eva and Hellström, Ann and Tornqvist, Kristina and Wallin, Agneta and Sunnqvist, Birgitta and Sandgren Hochhard, Karin and Lundgren, Pia and Al-Hawasi, Abbas and Teär Fahnehjelm, Kristina and Gränse, Lotta and Holmstrom, Gerd}},
  issn         = {{0007-1161}},
  keywords     = {{child health (paediatrics); epidemiology; retina; treatment other; vision}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{137--142}},
  publisher    = {{BMJ Publishing Group}},
  series       = {{British Journal of Ophthalmology}},
  title        = {{Ophthalmological outcome of 6.5 years children treated for retinopathy of prematurity : A Swedish register study}},
  url          = {{http://dx.doi.org/10.1136/bjo-2022-322022}},
  doi          = {{10.1136/bjo-2022-322022}},
  volume       = {{108}},
  year         = {{2024}},
}