Flow-injection immunoassays : Present and future
(1992) In Microchemical Journal 45(2). p.121-128- Abstract
The recent development of the flow-injection immunoassay (FIIA), beginning with one of the first publications in 1980 by Lim and Miller, has resulted in a growing field which combines the precise and reproducible timing of flow-injection analysis (FIA) with immunoassays to yield assays which are carried out in a nonequilibrium time frame. These often faster assay methods require small volumes of sample and reduced sample handling. The advancement of this field is briefly reviewed in this paper with respect to the general methods and detection schemes applied. A novel method utilizing sequential injection (SI) is also introduced. The method uses immunomagnetic beads to create a renewable reaction column which does not require in-line... (More)
The recent development of the flow-injection immunoassay (FIIA), beginning with one of the first publications in 1980 by Lim and Miller, has resulted in a growing field which combines the precise and reproducible timing of flow-injection analysis (FIA) with immunoassays to yield assays which are carried out in a nonequilibrium time frame. These often faster assay methods require small volumes of sample and reduced sample handling. The advancement of this field is briefly reviewed in this paper with respect to the general methods and detection schemes applied. A novel method utilizing sequential injection (SI) is also introduced. The method uses immunomagnetic beads to create a renewable reaction column which does not require in-line regeneration.
(Less)
- author
- Pollema, Cy H.
; Ruzicka, Jaromir
; Lernmark, Åke
LU
and Christian, Gary D.
- publishing date
- 1992-01-01
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Microchemical Journal
- volume
- 45
- issue
- 2
- pages
- 8 pages
- publisher
- Elsevier
- external identifiers
-
- scopus:0000007601
- ISSN
- 0026-265X
- DOI
- 10.1016/0026-265X(92)90003-L
- language
- English
- LU publication?
- no
- id
- 5e882680-4692-4b8b-b2da-ab59cd976b50
- date added to LUP
- 2019-09-11 09:34:48
- date last changed
- 2021-01-03 11:21:22
@article{5e882680-4692-4b8b-b2da-ab59cd976b50, abstract = {{<p>The recent development of the flow-injection immunoassay (FIIA), beginning with one of the first publications in 1980 by Lim and Miller, has resulted in a growing field which combines the precise and reproducible timing of flow-injection analysis (FIA) with immunoassays to yield assays which are carried out in a nonequilibrium time frame. These often faster assay methods require small volumes of sample and reduced sample handling. The advancement of this field is briefly reviewed in this paper with respect to the general methods and detection schemes applied. A novel method utilizing sequential injection (SI) is also introduced. The method uses immunomagnetic beads to create a renewable reaction column which does not require in-line regeneration.</p>}}, author = {{Pollema, Cy H. and Ruzicka, Jaromir and Lernmark, Åke and Christian, Gary D.}}, issn = {{0026-265X}}, language = {{eng}}, month = {{01}}, number = {{2}}, pages = {{121--128}}, publisher = {{Elsevier}}, series = {{Microchemical Journal}}, title = {{Flow-injection immunoassays : Present and future}}, url = {{http://dx.doi.org/10.1016/0026-265X(92)90003-L}}, doi = {{10.1016/0026-265X(92)90003-L}}, volume = {{45}}, year = {{1992}}, }