Familial malignant blood disease in the county of Jämtland, Sweden
(1987) In European Journal of Haematology 38(3). p.241-245- Abstract
In a material of 942 patients with malignant hematological disease, encompassing all diagnosed cases in the county of Jämtland in Sweden during a 22‐yr period, 36 families with multiple cases of such disease were found. Approximately 5% of the patients have at least one close relative who also suffers from a malignant hematological disease. An especially strong familial occurrence was found in the group of chronic lymphoproliferative diseases and it is concluded that this tendency comprises all diseases in the group, i.e. chronic lymphocytic leukemia, multiple myeloma and malignant lymphoma. In some families several cases of acute leukemia were present, and suggestions concerning immunological disturbances are made. In the group of... (More)
In a material of 942 patients with malignant hematological disease, encompassing all diagnosed cases in the county of Jämtland in Sweden during a 22‐yr period, 36 families with multiple cases of such disease were found. Approximately 5% of the patients have at least one close relative who also suffers from a malignant hematological disease. An especially strong familial occurrence was found in the group of chronic lymphoproliferative diseases and it is concluded that this tendency comprises all diseases in the group, i.e. chronic lymphocytic leukemia, multiple myeloma and malignant lymphoma. In some families several cases of acute leukemia were present, and suggestions concerning immunological disturbances are made. In the group of chronic myeloproliferative diseases familial factors do not seem to play an important. part, with the possible exception of polycythemia vera. Both heredity and common environmental agents must be considered as possible etiologic factors.
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- author
- Eriksson, Mikael LU and Bergström, Ingmar
- publishing date
- 1987-01-01
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- familial occurrence, heredity, leukemia, malignant lymphoma, multiple myeloma, polycythemia Vera
- in
- European Journal of Haematology
- volume
- 38
- issue
- 3
- pages
- 241 - 245
- publisher
- Wiley-Blackwell
- external identifiers
-
- scopus:0023300922
- pmid:3595812
- ISSN
- 0902-4441
- DOI
- 10.1111/j.1600-0609.1987.tb01170.x
- language
- English
- LU publication?
- no
- id
- 63edb2c9-4f57-4ff8-8717-07685cdb4757
- date added to LUP
- 2020-03-26 16:14:00
- date last changed
- 2024-01-02 07:46:13
@article{63edb2c9-4f57-4ff8-8717-07685cdb4757, abstract = {{<p>In a material of 942 patients with malignant hematological disease, encompassing all diagnosed cases in the county of Jämtland in Sweden during a 22‐yr period, 36 families with multiple cases of such disease were found. Approximately 5% of the patients have at least one close relative who also suffers from a malignant hematological disease. An especially strong familial occurrence was found in the group of chronic lymphoproliferative diseases and it is concluded that this tendency comprises all diseases in the group, i.e. chronic lymphocytic leukemia, multiple myeloma and malignant lymphoma. In some families several cases of acute leukemia were present, and suggestions concerning immunological disturbances are made. In the group of chronic myeloproliferative diseases familial factors do not seem to play an important. part, with the possible exception of polycythemia vera. Both heredity and common environmental agents must be considered as possible etiologic factors.</p>}}, author = {{Eriksson, Mikael and Bergström, Ingmar}}, issn = {{0902-4441}}, keywords = {{familial occurrence; heredity; leukemia; malignant lymphoma; multiple myeloma; polycythemia Vera}}, language = {{eng}}, month = {{01}}, number = {{3}}, pages = {{241--245}}, publisher = {{Wiley-Blackwell}}, series = {{European Journal of Haematology}}, title = {{Familial malignant blood disease in the county of Jämtland, Sweden}}, url = {{http://dx.doi.org/10.1111/j.1600-0609.1987.tb01170.x}}, doi = {{10.1111/j.1600-0609.1987.tb01170.x}}, volume = {{38}}, year = {{1987}}, }