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Low usefulness of reporting tonsillar PCR Ct-values in pharyngeal infections with Fusobacterium necrophorum

Nygren, David LU orcid ; Wasserstrom, Lisa LU ; Torisson, Gustav LU orcid and Holm, Karin LU (2024) In Anaerobe 86.
Abstract

Tonsillar Fusobacterium necrophorum PCR Ct-values were higher in participants with asymptomatic tonsillar carriage than patients with pharyngeal infections. However, Ct-values were not associated with severity of disease or predictive of development of complications and hence lacked clinical usefulness. The reporting of F. necrophorum Ct-values in clinical samples is not recommended.

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author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Humans, Fusobacterium necrophorum/genetics, Fusobacterium Infections/microbiology, Male, Polymerase Chain Reaction/methods, Female, Adult, Middle Aged, Palatine Tonsil/microbiology, Young Adult, Adolescent, Aged, Tomography, X-Ray Computed, Carrier State/microbiology
in
Anaerobe
volume
86
article number
102831
publisher
Elsevier
external identifiers
  • scopus:85187501041
  • pmid:38369049
ISSN
1095-8274
DOI
10.1016/j.anaerobe.2024.102831
language
English
LU publication?
yes
additional info
Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.
id
68acb225-92e4-4248-92c9-364c4a86c9e4
date added to LUP
2024-05-14 12:01:15
date last changed
2025-01-27 14:56:58
@article{68acb225-92e4-4248-92c9-364c4a86c9e4,
  abstract     = {{<p>Tonsillar Fusobacterium necrophorum PCR Ct-values were higher in participants with asymptomatic tonsillar carriage than patients with pharyngeal infections. However, Ct-values were not associated with severity of disease or predictive of development of complications and hence lacked clinical usefulness. The reporting of F. necrophorum Ct-values in clinical samples is not recommended.</p>}},
  author       = {{Nygren, David and Wasserstrom, Lisa and Torisson, Gustav and Holm, Karin}},
  issn         = {{1095-8274}},
  keywords     = {{Humans; Fusobacterium necrophorum/genetics; Fusobacterium Infections/microbiology; Male; Polymerase Chain Reaction/methods; Female; Adult; Middle Aged; Palatine Tonsil/microbiology; Young Adult; Adolescent; Aged; Tomography, X-Ray Computed; Carrier State/microbiology}},
  language     = {{eng}},
  publisher    = {{Elsevier}},
  series       = {{Anaerobe}},
  title        = {{Low usefulness of reporting tonsillar PCR Ct-values in pharyngeal infections with Fusobacterium necrophorum}},
  url          = {{http://dx.doi.org/10.1016/j.anaerobe.2024.102831}},
  doi          = {{10.1016/j.anaerobe.2024.102831}},
  volume       = {{86}},
  year         = {{2024}},
}